iPTMnet Report Q7L0J3 SV2A

Protein Information

UniProt AC / UniProt ID	Q7L0J3 / SV2A_HUMAN
Protein Name	Synaptic vesicle glycoprotein 2A
Gene Name	Name: SV2A Synonyms:KIAA0736;ORFNames:PSEC0174;
Organism	Homo sapiens (Human)

PRO ID	PR:Q7L0J3 DAG View
PRO Name	synaptic vesicle glycoprotein 2A (human)
Definition	A synaptic vesicle glycoprotein 2A that is encoded in the genome of human.
Short Label	hSV2A
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q7L0J3 (SV2A) as Substrate

Condensed View

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position K32 Y41 S42 S45 S47 S62 Y65 Y66 T71 S80 S81 T84 Y94 Y98 R123 S127 K143 Y212 K366 K375 S393 T395 S411 Y480 K485 K515 N573	PTM Type Select all Methylation N-Glycosylation Phosphorylation Ubiquitination	PTM Enzyme Select all Q6IQ55 (TTBK2)	Score Select all 1 2 4	Source Select all GlyGen PhosphoSitePlus UniProt phospho.ELM	PMID
K32	Ubiquitination		score1	PhosphoSitePlus
Y41	Phosphorylation		score1	PhosphoSitePlus
S42	Phosphorylation		score2	PhosphoSitePlus	25673844
S42	Phosphorylation	Q6IQ55 (TTBK2)	score2	PhosphoSitePlus	25673844
S45	Phosphorylation		score2	PhosphoSitePlus	25673844
S45	Phosphorylation	Q6IQ55 (TTBK2)	score2	PhosphoSitePlus	25673844
S47	Phosphorylation		score2	PhosphoSitePlus	25673844
S47	Phosphorylation	Q6IQ55 (TTBK2)	score2	PhosphoSitePlus	25673844
S62	Phosphorylation		score1	PhosphoSitePlus
Y65	Phosphorylation		score1	PhosphoSitePlus
Y66	Phosphorylation		score1	PhosphoSitePlus
T71	Phosphorylation		score1	PhosphoSitePlus
S80	Phosphorylation		score4	PhosphoSitePlus UniProt	19690332, 25673844
S80	Phosphorylation	Q6IQ55 (TTBK2)	score2	PhosphoSitePlus	25673844
S81	Phosphorylation		score4	PhosphoSitePlus UniProt	19690332, 25673844
S81	Phosphorylation	Q6IQ55 (TTBK2)	score2	PhosphoSitePlus	25673844
T84	Phosphorylation		score4	PhosphoSitePlus UniProt	19690332, 25673844
T84	Phosphorylation	Q6IQ55 (TTBK2)	score2	PhosphoSitePlus	25673844
Y94	Phosphorylation		score1	PhosphoSitePlus
Y98	Phosphorylation		score1	PhosphoSitePlus
R123	Methylation		score1	PhosphoSitePlus
S127	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	15822905
K143	Ubiquitination		score1	PhosphoSitePlus
Y212	Phosphorylation		score1	PhosphoSitePlus
K366	Ubiquitination		score1	PhosphoSitePlus
K375	Ubiquitination		score1	PhosphoSitePlus
S393	Phosphorylation		score1	PhosphoSitePlus
T395	Phosphorylation		score1	PhosphoSitePlus
S411	Phosphorylation		score1	PhosphoSitePlus
Y480	Phosphorylation		score1	PhosphoSitePlus
K485	Ubiquitination		score1	PhosphoSitePlus
K515	Ubiquitination		score1	PhosphoSitePlus
N573	N-Glycosylation		score1	GlyGen	24190977

Search:

	Site Select all By amino acid All Serine By position S127	PTM Type Select all Phosphorylation	PTM Enzyme Select all	Score Select all 0	Source Select all HPRD	PMID
	S127	Phosphorylation		score0	HPRD	18510355

PTM sites affected in variants

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position S42 S45 S47 T71 Y98 S127 K143 T395 S411 K485	Variant Select all A71 C47 E143 E485 F42 H98 I127 I395 L411 L45 N71	Source Select all Biomuta	Disease [Sample source] Select all DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
S42	F42	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
S45	L45	Biomuta	DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
S47	C47	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]
T71	N71	Biomuta	DOID:3571 / liver cancer [ cosmic ]
T71	A71	Biomuta	DOID:10534 / stomach cancer [ cosmic ]
Y98	H98	Biomuta	DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S127	I127	Biomuta	DOID:2531 / hematologic cancer [ cosmic ]
K143	E143	Biomuta	DOID:10283 / prostate cancer [ cosmic, icgc ]
T395	I395	Biomuta	DOID:3571 / liver cancer [ cosmic ]
S411	L411	Biomuta	DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
K485	E485	Biomuta	DOID:11054 / urinary bladder cancer [ cosmic, icgc ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for Q7L0J3 (SV2A)

Protein Information

Interactive Sequence View

Q7L0J3 (SV2A) as Substrate

PTM sites affected in variants