Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7L0J3 / SV2A_HUMAN
Protein Name Synaptic vesicle glycoprotein 2A
Gene Name Name: SV2A
Synonyms:KIAA0736;ORFNames:PSEC0174;
Organism Homo sapiens (Human)

PRO ID PR:Q7L0J3
DAG View
PRO Name synaptic vesicle glycoprotein 2A (human)
Definition A synaptic vesicle glycoprotein 2A that is encoded in the genome of human.
Short Label hSV2A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7L0J3 (SV2A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K32 Ubiquitination PhosphoSitePlus
Y41 Phosphorylation PhosphoSitePlus
S42 Phosphorylation Q6IQ55 (TTBK2) PhosphoSitePlus 25673844
S45 Phosphorylation Q6IQ55 (TTBK2) PhosphoSitePlus 25673844
S47 Phosphorylation Q6IQ55 (TTBK2) PhosphoSitePlus 25673844
S62 Phosphorylation PhosphoSitePlus
Y65 Phosphorylation PhosphoSitePlus
Y66 Phosphorylation PhosphoSitePlus
T71 Phosphorylation PhosphoSitePlus
S80 Phosphorylation Q6IQ55 (TTBK2) PhosphoSitePlus   UniProt 19690332, 25673844
S81 Phosphorylation Q6IQ55 (TTBK2) PhosphoSitePlus   UniProt 19690332, 25673844
T84 Phosphorylation Q6IQ55 (TTBK2) PhosphoSitePlus   UniProt 19690332, 25673844
Y94 Phosphorylation PhosphoSitePlus
Y98 Phosphorylation PhosphoSitePlus
R123 Methylation PhosphoSitePlus
S127 Phosphorylation phospho.ELM   PhosphoSitePlus 15822905
K143 Ubiquitination PhosphoSitePlus
Y212 Phosphorylation PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
S393 Phosphorylation PhosphoSitePlus
T395 Phosphorylation PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus
Y480 Phosphorylation PhosphoSitePlus
K485 Ubiquitination PhosphoSitePlus
K515 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S127 Phosphorylation HPRD 18510355


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S42 F42 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ]
S45 L45 Biomuta DOID:8618 / oral cavity cancer [ icgc ]
S47 C47 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
T71 N71 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y98 H98 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
S127 I127 Biomuta DOID:2531 / hematologic cancer [ icgc ]
K143 E143 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
T395 I395 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S411 L411 Biomuta DOID:10534 / stomach cancer [ icgc, tcga ]
K485 E485 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]