iPTMnet Report for Q76I76 (SSH2)
Protein Information
UniProt AC / UniProt ID | Q76I76 / SSH2_HUMAN |
Protein Name | Protein phosphatase Slingshot homolog 2 |
Gene Name | Name: SSH2 Synonyms:KIAA1725,SSH2L; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q76I76 |
PRO Name | protein phosphatase Slingshot homolog 2 (human) |
Definition | A protein phosphatase Slingshot homolog 2 that is encoded in the genome of human. |
Short Label | hSSH2 |
Category | organism-gene |
Q76I76 (SSH2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S25 | Phosphorylation | score1 | PhosphoSitePlus | |||
S36 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S40 | Phosphorylation | score1 | PhosphoSitePlus | |||
S63 | Phosphorylation | score1 | PhosphoSitePlus | |||
K265 | Ubiquitination | score1 | PhosphoSitePlus | |||
K273 | Ubiquitination | score1 | PhosphoSitePlus | |||
S399 | Phosphorylation | score1 | PhosphoSitePlus | |||
S401 | Phosphorylation | score1 | PhosphoSitePlus | |||
T402 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y406 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y411 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y419 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y421 | Phosphorylation | score1 | PhosphoSitePlus | |||
K423 | Ubiquitination | score1 | PhosphoSitePlus | |||
K430 | Ubiquitination | score1 | PhosphoSitePlus | |||
K450 | Ubiquitination | score1 | PhosphoSitePlus | |||
K455 | Ubiquitination | score1 | PhosphoSitePlus | |||
S459 | Phosphorylation | score1 | PhosphoSitePlus | |||
S461 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983 | ||
S463 | Phosphorylation | score1 | PhosphoSitePlus | |||
S466 | Phosphorylation | score1 | PhosphoSitePlus | |||
K482 | Ubiquitination | score1 | PhosphoSitePlus | |||
T486 | Phosphorylation | score1 | PhosphoSitePlus | |||
S487 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
K588 | Ubiquitination | score1 | PhosphoSitePlus | |||
S654 | Phosphorylation | score1 | PhosphoSitePlus | |||
T666 | Phosphorylation | score1 | PhosphoSitePlus | |||
S672 | Phosphorylation | score1 | PhosphoSitePlus | |||
S690 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
S690 | Phosphorylation | score1 | PhosphoSitePlus | |||
S706 | Phosphorylation | score1 | PhosphoSitePlus | |||
S734 | Phosphorylation | score1 | PhosphoSitePlus | |||
T754 | Phosphorylation | score1 | PhosphoSitePlus | |||
S758 | Phosphorylation | score1 | PhosphoSitePlus | |||
S760 | Phosphorylation | score1 | PhosphoSitePlus | |||
T779 | Phosphorylation | score1 | PhosphoSitePlus | |||
K782 | Ubiquitination | score1 | PhosphoSitePlus | |||
S784 | Phosphorylation | score1 | PhosphoSitePlus | |||
T795 | Phosphorylation | score1 | PhosphoSitePlus | |||
T870 | Phosphorylation | score1 | PhosphoSitePlus | |||
S899 | Phosphorylation | score1 | PhosphoSitePlus | |||
S931 | Phosphorylation | score1 | PhosphoSitePlus | |||
K985 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1187 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1191 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1216 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1217 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S1218 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1227 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1249 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1252 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1259 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1283 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1297 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1352 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1356 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1408 | Acetylation | score1 | PhosphoSitePlus | |||
K1412 | Acetylation | score1 | PhosphoSitePlus | |||
K1413 | Acetylation | score1 | PhosphoSitePlus | |||
T1422 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 19690332 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S36 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S461 | Phosphorylation | score0 | HPRD | 17081983 | ||
S487 | Phosphorylation | score0 | HPRD | 19413330, 19664994 | ||
S734 | Phosphorylation | score0 | HPRD | 20068231 | ||
S1216 | Phosphorylation | score0 | HPRD | 20068231 | ||
S1217 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
S1218 | Phosphorylation | score0 | HPRD | 20068231 | ||
S1227 | Phosphorylation | score0 | HPRD | 20068231 | ||
T1422 | Phosphorylation | score0 | HPRD | 18669648, 15345747 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S36 | I36 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S36 | R36 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S63 | R63 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K265 | Q265 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S399 | L399 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S399 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
S401 | P401 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
Y411 | N411 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
Y419 | C419 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S466 | L466 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S706 | I706 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S784 | N784 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S784 | R784 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S1259 | Y1259 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T1422 | I1422 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |