iPTMnet Report for Q70UQ0 (IKBIP)
Protein Information
| UniProt AC / UniProt ID | Q70UQ0 / IKIP_HUMAN |
| Protein Name | Inhibitor of nuclear factor kappa-B kinase-interacting protein |
| Gene Name | Name: IKBIP Synonyms:IKIP; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q70UQ0 |
| PRO Name | inhibitor of nuclear factor kappa-B kinase-interacting protein (human) |
| Definition | An inhibitor of nuclear factor kappa-B kinase-interacting protein that is encoded in the genome of human. |
| Short Label | hIKBIP |
| Category | organism-gene |
DAG ViewQ70UQ0 (IKBIP) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S24 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y76 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N144 | N-Glycosylation | score2 | GlyGen UniProt | 29671580, 19159218, 24190977 | ||
| N145 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| S183 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T187 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S191 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T193 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K212 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S220 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S221 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T225 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T245 | O-Glycosylation | score1 | GlyGen | 33465208 | ||
| T247 | O-Glycosylation | score1 | GlyGen | 33465208 | ||
| T247 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T257 | O-Glycosylation | score1 | GlyGen | 33214551, 34725712, 33465208, ... | ||
| N328 | N-Glycosylation | score2 | GlyGen UniProt | 29741879, 19159218, 24190977 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K203 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K240 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K258 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K295 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y330 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S10 | L10 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K212 | R212 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K212 | N212 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| T225 | I225 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
| T245 | M245 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] | |
| K295 | N295 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |
