iPTMnet Report for Q70UQ0 (IKBIP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q70UQ0 / IKIP_HUMAN
Protein Name Inhibitor of nuclear factor kappa-B kinase-interacting protein
Gene Name Name: IKBIP
Synonyms:IKIP;
Organism Homo sapiens (Human)

PRO ID PR:Q70UQ0
DAG View
PRO Name inhibitor of nuclear factor kappa-B kinase-interacting protein (human)
Definition An inhibitor of nuclear factor kappa-B kinase-interacting protein that is encoded in the genome of human.
Short Label hIKBIP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q70UQ0 (IKBIP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
Y76 Phosphorylation PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
N144 N-Glycosylation GlyGen   UniProt 29671580, 19159218, 24190977
N145 N-Glycosylation GlyGen 24190977
S183 Phosphorylation PhosphoSitePlus
T187 Phosphorylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
T193 Phosphorylation PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
T225 Phosphorylation PhosphoSitePlus
T245 O-Glycosylation GlyGen 33465208
T247 O-Glycosylation GlyGen 33465208
T247 Phosphorylation PhosphoSitePlus
T257 O-Glycosylation GlyGen 33214551, 34725712, 33465208, ...34019948, 22661428
N328 N-Glycosylation GlyGen   UniProt 29741879, 19159218, 24190977
Site PTM Type PTM Enzyme Score Source PMID
N144 N-Glycosylation PRO 29671580
Site PTM Type PTM Enzyme Score Source PMID
K203 Ubiquitination PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
Y330 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S10 L10 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K212 R212 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K212 N212 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T225 I225 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
T245 M245 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ]
K295 N295 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]