iPTMnet Report for Q6Y1H2 (HACD2)
Protein Information
UniProt AC / UniProt ID | Q6Y1H2 / HACD2_HUMAN |
Protein Name | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 |
Gene Name | Name: HACD2 Synonyms:PTPLB; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q6Y1H2 |
PRO Name | very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (human) |
Definition | A very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 that is encoded in the genome of human. |
Short Label | hHACD2 |
Category | organism-gene |
Q6Y1H2 (HACD2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 25732826 | ||
T7 | Phosphorylation | score1 | PhosphoSitePlus | |||
K11 | Ubiquitination | score1 | PhosphoSitePlus | |||
S181 | Phosphorylation | score1 | PhosphoSitePlus | |||
K251 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K11 | E11 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |