Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6Y1H2 / HACD2_HUMAN
Protein Name Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2
Gene Name Name: HACD2
Synonyms:PTPLB;
Organism Homo sapiens (Human)

PRO ID PR:Q6Y1H2
DAG View
PRO Name very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 2 (human)
Definition A very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 2 that is encoded in the genome of human.
Short Label hHACD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6Y1H2 (HACD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 25732826
T7 Phosphorylation PhosphoSitePlus
K11 Ubiquitination PhosphoSitePlus
S181 Phosphorylation PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K11 E11 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]