iPTMnet Report for Q6VAB6 (KSR2)
Protein Information
| UniProt AC / UniProt ID | Q6VAB6 / KSR2_HUMAN |
| Protein Name | Kinase suppressor of Ras 2 |
| Gene Name | Name: KSR2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q6VAB6 |
| PRO Name | kinase suppressor of Ras 2 (human) |
| Definition | A kinase suppressor of Ras 2 that is encoded in the genome of human. |
| Short Label | hKSR2 |
| Category | organism-gene |
DAG ViewQ6VAB6 (KSR2) as Substrate
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Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S34 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K44 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T260 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T264 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T269 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T270 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T272 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T276 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K281 | Acetylation | score1 | PhosphoSitePlus | |||
| T290 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S294 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T306 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S311 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S313 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S347 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S394 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S399 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S474 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T497 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y566 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y794 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T802 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S808 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K923 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S939 | Phosphorylation | score1 | PhosphoSitePlus |
Q6VAB6 (KSR2) as PTM Enzyme
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T270 | I270 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T276 | M276 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
| K281 | T281 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
| T290 | I290 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S294 | F294 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T306 | N306 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| S311 | N311 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S313 | Y313 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S347 | R347 | Biomuta | DOID:1324 / lung cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] | |
| S399 | F399 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S474 | F474 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T802 | M802 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
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