iPTMnet Report for Q6P1R4 (DUS1L)
Protein Information
UniProt AC / UniProt ID | Q6P1R4 / DUS1L_HUMAN |
Protein Name | tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like |
Gene Name | Name: DUS1L |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q6P1R4 |
PRO Name | tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like (human) |
Definition | A tRNA-dihydrouridine synthase 1-like that is encoded in the genome of human. |
Short Label | hDUS1L |
Category | organism-gene |
Q6P1R4 (DUS1L) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K3 | Sumoylation | score1 | PhosphoSitePlus | |||
Y45 | Phosphorylation | score1 | PhosphoSitePlus | |||
K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
K147 | Ubiquitination | score1 | PhosphoSitePlus | |||
K156 | Ubiquitination | score1 | PhosphoSitePlus | |||
K166 | Ubiquitination | score1 | PhosphoSitePlus | |||
K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
K296 | Ubiquitination | score1 | PhosphoSitePlus | |||
K309 | Ubiquitination | score1 | PhosphoSitePlus | |||
S317 | Phosphorylation | score1 | PhosphoSitePlus | |||
K323 | Ubiquitination | score1 | PhosphoSitePlus | |||
C426 | Methylation | score1 | IEDB | 31844290 | ||
T460 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19413330 | ||
S465 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19413330 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y45 | C45 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K156 | N156 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
K195 | T195 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S465 | F465 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |