iPTMnet Report for Q6P1R4 (DUS1L)
Protein Information
| UniProt AC / UniProt ID | Q6P1R4 / DUS1L_HUMAN |
| Protein Name | tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like |
| Gene Name | Name: DUS1L |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q6P1R4 |
| PRO Name | tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like (human) |
| Definition | A tRNA-dihydrouridine synthase 1-like that is encoded in the genome of human. |
| Short Label | hDUS1L |
| Category | organism-gene |
Q6P1R4 (DUS1L) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K3 | Sumoylation | score1 | PhosphoSitePlus | |||
| Y45 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K147 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K156 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K166 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K296 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K309 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S317 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K323 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C426 | Methylation | score1 | IEDB | 31844290 | ||
| T460 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19413330 | ||
| S465 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19413330 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y45 | C45 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K156 | N156 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| K195 | T195 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S465 | F465 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
DAG View