iPTMnet Report for Q6J4K2 (SLC8B1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6J4K2 / NCLX_HUMAN
Protein Name Mitochondrial sodium/calcium exchanger protein precursor
Gene Name Name: SLC8B1
Synonyms:NCKX6;
Organism Homo sapiens (Human)

PRO ID PR:Q6J4K2
DAG View
PRO Name mitochondrial sodium/calcium exchanger protein (human)
Definition A mitochondrial sodium/calcium exchanger protein that is encoded in the genome of human.
Short Label hSLC8B1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6J4K2 (SLC8B1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N60 N-Glycosylation GlyGen 24190977
T70 Phosphorylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
Y233 Phosphorylation PhosphoSitePlus
Y240 Phosphorylation PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 26440884
S258 Phosphorylation P17612 (PRKACA) PhosphoSitePlus 26440884
K316 Ubiquitination PhosphoSitePlus
T456 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T456 Phosphorylation HPRD 20058876


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y240 C240 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S258 F258 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
T456 S456 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]