Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6J4K2 / NCLX_HUMAN
Protein Name Mitochondrial sodium/calcium exchanger protein precursor
Gene Name Name: SLC8B1
Synonyms:NCKX6;
Organism Homo sapiens (Human)

PRO ID PR:Q6J4K2
DAG View
PRO Name mitochondrial sodium/calcium exchanger protein (human)
Definition A mitochondrial sodium/calcium exchanger protein that is encoded in the genome of human.
Short Label hSLC8B1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6J4K2 (SLC8B1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N60 N-Glycosylation GlyGen 24190977
T70 Phosphorylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
Y233 Phosphorylation PhosphoSitePlus
Y240 Phosphorylation PhosphoSitePlus
S258 Phosphorylation P17612 (PRKACA) PhosphoSitePlus   RLIMS-P   UniProt 26440884
K316 Ubiquitination PhosphoSitePlus
T456 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T456 Phosphorylation HPRD 20058876


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y240 C240 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
S258 F258 Biomuta DOID:4362 / cervical cancer [ tcga ]
T456 S456 Biomuta DOID:1324 / lung cancer [ tcga ]