iPTMnet Report for Q6IA69 (NADSYN1)
Protein Information
UniProt AC / UniProt ID | Q6IA69 / NADE_HUMAN |
Protein Name | Glutamine-dependent NAD(+) synthetase |
Gene Name | Name: NADSYN1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q6IA69 |
PRO Name | glutamine-dependent NAD(+) synthetase (human) |
Definition | A glutamine-dependent NAD(+) synthetase that is encoded in the genome of human. |
Short Label | hNADSYN1 |
Category | organism-gene |
Q6IA69 (NADSYN1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
S29 | Phosphorylation | score1 | PhosphoSitePlus | |||
T211 | Phosphorylation | score1 | PhosphoSitePlus | |||
T217 | Phosphorylation | score1 | PhosphoSitePlus | |||
T220 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y227 | Phosphorylation | score1 | PhosphoSitePlus | |||
S308 | Phosphorylation | score1 | IEDB | 35494241 | ||
K421 | Ubiquitination | score1 | PhosphoSitePlus | |||
S423 | Phosphorylation | score1 | PhosphoSitePlus | |||
S424 | Phosphorylation | score1 | PhosphoSitePlus | |||
T427 | Phosphorylation | score1 | PhosphoSitePlus | |||
T429 | Phosphorylation | score1 | PhosphoSitePlus | |||
T462 | Phosphorylation | score1 | PhosphoSitePlus | |||
K642 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y643 | Phosphorylation | score1 | PhosphoSitePlus | |||
S644 | Phosphorylation | score1 | PhosphoSitePlus | |||
K649 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y657 | Phosphorylation | score1 | PhosphoSitePlus | |||
S701 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y227 | H227 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S308 | L308 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
S423 | T423 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S424 | F424 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T427 | M427 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K642 | N642 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
Y643 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
Y657 | H657 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] |