iPTMnet Report for Q6EMB2 (TTLL5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q6EMB2 / TTLL5_HUMAN
Protein Name Tubulin polyglutamylase TTLL5
Gene Name Name: TTLL5
Synonyms:KIAA0998,STAMP;
Organism Homo sapiens (Human)

PRO ID PR:Q6EMB2
DAG View
PRO Name tubulin polyglutamylase TTLL5 (human)
Definition A tubulin polyglutamylase TTLL5 that is encoded in the genome of human.
Short Label hTTLL5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q6EMB2 (TTLL5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K118 Ubiquitination PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
T129 Phosphorylation PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
Y227 Phosphorylation PhosphoSitePlus
Y233 Phosphorylation PhosphoSitePlus
Y239 Phosphorylation PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
T414 Phosphorylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
K440 Ubiquitination PhosphoSitePlus
K449 Acetylation PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
K467 Acetylation PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
Y542 Phosphorylation PhosphoSitePlus
S559 Phosphorylation PhosphoSitePlus
T581 Phosphorylation PhosphoSitePlus
K617 Ubiquitination PhosphoSitePlus
S621 Phosphorylation PhosphoSitePlus
K643 Ubiquitination PhosphoSitePlus
K649 Ubiquitination PhosphoSitePlus
K658 Ubiquitination PhosphoSitePlus
S723 Phosphorylation PhosphoSitePlus
S736 Phosphorylation PhosphoSitePlus
Y759 Phosphorylation PhosphoSitePlus
S796 Phosphorylation PhosphoSitePlus
K810 Ubiquitination PhosphoSitePlus
K812 Ubiquitination PhosphoSitePlus
K823 Ubiquitination PhosphoSitePlus
K826 Ubiquitination PhosphoSitePlus
K837 Ubiquitination PhosphoSitePlus
K865 Ubiquitination PhosphoSitePlus
K875 Ubiquitination PhosphoSitePlus
K878 Ubiquitination PhosphoSitePlus
Y881 Phosphorylation PhosphoSitePlus
K994 Ubiquitination PhosphoSitePlus
S997 Phosphorylation PhosphoSitePlus
K1002 Ubiquitination PhosphoSitePlus
K1009 Ubiquitination PhosphoSitePlus
K1012 Ubiquitination PhosphoSitePlus
Y1020 Phosphorylation PhosphoSitePlus
K1022 Ubiquitination PhosphoSitePlus
K1039 Ubiquitination PhosphoSitePlus
K1159 Ubiquitination PhosphoSitePlus
S1199 Phosphorylation PhosphoSitePlus
S1200 Phosphorylation PhosphoSitePlus
K1207 Ubiquitination PhosphoSitePlus
S1221 O-Glycosylation GlyGen 30059200


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y233 N233 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y241 F241 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K258 N258 Biomuta DOID:363 / uterine cancer [ icgc ]
K274 N274 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T414 P414 Biomuta DOID:1612 / breast cancer [ cosmic ]
T581 I581 Biomuta DOID:363 / uterine cancer [ icgc ]
K658 T658 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S723 L723 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K810 N810 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K823 N823 Biomuta DOID:363 / uterine cancer [ icgc ]
K878 T878 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S997 L997 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
K1002 T1002 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1039 N1039 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1199 F1199 Biomuta DOID:4159 / skin cancer [ cosmic ]