iPTMnet Report for Q6EMB2 (TTLL5)
Protein Information
UniProt AC / UniProt ID | Q6EMB2 / TTLL5_HUMAN |
Protein Name | Tubulin polyglutamylase TTLL5 |
Gene Name | Name: TTLL5 Synonyms:KIAA0998,STAMP; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q6EMB2 |
PRO Name | tubulin polyglutamylase TTLL5 (human) |
Definition | A tubulin polyglutamylase TTLL5 that is encoded in the genome of human. |
Short Label | hTTLL5 |
Category | organism-gene |
Q6EMB2 (TTLL5) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K118 | Ubiquitination | score1 | PhosphoSitePlus | |||
S125 | Phosphorylation | score1 | PhosphoSitePlus | |||
T129 | Phosphorylation | score1 | PhosphoSitePlus | |||
K180 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y227 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y233 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y239 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y241 | Phosphorylation | score1 | PhosphoSitePlus | |||
K258 | Ubiquitination | score1 | PhosphoSitePlus | |||
K274 | Ubiquitination | score1 | PhosphoSitePlus | |||
K275 | Ubiquitination | score1 | PhosphoSitePlus | |||
T414 | Phosphorylation | score1 | PhosphoSitePlus | |||
S433 | Phosphorylation | score1 | PhosphoSitePlus | |||
S435 | Phosphorylation | score1 | PhosphoSitePlus | |||
K440 | Ubiquitination | score1 | PhosphoSitePlus | |||
K449 | Acetylation | score1 | PhosphoSitePlus | |||
K453 | Ubiquitination | score1 | PhosphoSitePlus | |||
K467 | Acetylation | score1 | PhosphoSitePlus | |||
K534 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y542 | Phosphorylation | score1 | PhosphoSitePlus | |||
S559 | Phosphorylation | score1 | PhosphoSitePlus | |||
T581 | Phosphorylation | score1 | PhosphoSitePlus | |||
K617 | Ubiquitination | score1 | PhosphoSitePlus | |||
S621 | Phosphorylation | score1 | PhosphoSitePlus | |||
K643 | Ubiquitination | score1 | PhosphoSitePlus | |||
K649 | Ubiquitination | score1 | PhosphoSitePlus | |||
K658 | Ubiquitination | score1 | PhosphoSitePlus | |||
S723 | Phosphorylation | score1 | PhosphoSitePlus | |||
S736 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y759 | Phosphorylation | score1 | PhosphoSitePlus | |||
S796 | Phosphorylation | score1 | PhosphoSitePlus | |||
K810 | Ubiquitination | score1 | PhosphoSitePlus | |||
K812 | Ubiquitination | score1 | PhosphoSitePlus | |||
K823 | Ubiquitination | score1 | PhosphoSitePlus | |||
K826 | Ubiquitination | score1 | PhosphoSitePlus | |||
K837 | Ubiquitination | score1 | PhosphoSitePlus | |||
K865 | Ubiquitination | score1 | PhosphoSitePlus | |||
K875 | Ubiquitination | score1 | PhosphoSitePlus | |||
K878 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y881 | Phosphorylation | score1 | PhosphoSitePlus | |||
K994 | Ubiquitination | score1 | PhosphoSitePlus | |||
S997 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1002 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1009 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1012 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y1020 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1022 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1039 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1159 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1199 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1200 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1207 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1221 | O-Glycosylation | score1 | GlyGen | 30059200 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y233 | N233 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y241 | F241 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K258 | N258 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K274 | N274 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
T414 | P414 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
T581 | I581 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K658 | T658 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S723 | L723 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
K810 | N810 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
K823 | N823 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K878 | T878 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S997 | L997 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
K1002 | T1002 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K1039 | N1039 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S1199 | F1199 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |