iPTMnet Report for Q658P3 (STEAP3)
Protein Information
| UniProt AC / UniProt ID | Q658P3 / STEA3_HUMAN |
| Protein Name | Metalloreductase STEAP3 |
| Gene Name | Name: STEAP3 Synonyms:TSAP6; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q658P3 |
| PRO Name | metalloreductase STEAP3 (human) |
| Definition | A metalloreductase STEAP3 that is encoded in the genome of human. |
| Short Label | hSTEAP3 |
| Category | organism-gene |
Q658P3 (STEAP3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K7 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S11 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S17 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17081983, 24275569 | ||
| S19 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S20 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| K23 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K30 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T141 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y239 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S243 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N256 | N-Glycosylation | score3 | GlyGen UniProt | 22624035 | ||
| Y288 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y331 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K339 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N344 | N-Glycosylation | score3 | GlyGen UniProt | 22624035 | ||
| S469 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T470 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K472 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T474 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| T477 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K484 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S486 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S17 | Phosphorylation | score0 | HPRD | 19651622, 20166139, 18578522, ... | ||
| S19 | Phosphorylation | score0 | HPRD | 19651622, 20166139, 17081983 | ||
| S20 | Phosphorylation | score0 | HPRD | 19651622, 18578522, 17081983 | ||
| Y239 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S243 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S469 | Phosphorylation | score0 | HPRD | 18578522 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S27 | Phosphorylation | score0 | HPRD | 19651622, 20166139, 18578522, ... | ||
| S29 | Phosphorylation | score0 | HPRD | 19651622, 20166139, 17081983 | ||
| S30 | Phosphorylation | score0 | HPRD | 19651622, 18578522, 17081983 | ||
| Y249 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S253 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S479 | Phosphorylation | score0 | HPRD | 18578522 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S17 | R17 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S27 | R27 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S42 | F42 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S469 | N469 | Biomuta | DOID:4362 / cervical cancer [ cosmic ] | |
| S479 | N479 | Biomuta | DOID:4362 / cervical cancer [ cosmic ] |
DAG View