Protein Information

Cytoscape View


UniProt AC / UniProt ID Q658P3 / STEA3_HUMAN
Protein Name Metalloreductase STEAP3
Gene Name Name: STEAP3
Synonyms:TSAP6;
Organism Homo sapiens (Human)

PRO ID PR:Q658P3
DAG View
PRO Name metalloreductase STEAP3 (human)
Definition A metalloreductase STEAP3 that is encoded in the genome of human.
Short Label hSTEAP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q658P3 (STEAP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Ubiquitination PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus   UniProt 24275569
S17 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 24275569
S19 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus   UniProt 24275569
K23 Ubiquitination PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
T141 Phosphorylation PhosphoSitePlus
Y239 Phosphorylation PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
N256 N-Glycosylation GlyGen   UniProt 22624035
Y288 Phosphorylation PhosphoSitePlus
Y331 Phosphorylation PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
N344 N-Glycosylation GlyGen   UniProt 22624035
S469 Phosphorylation PhosphoSitePlus
T470 Phosphorylation PhosphoSitePlus
K472 Ubiquitination PhosphoSitePlus
T474 Phosphorylation PhosphoSitePlus   UniProt 24275569
T477 Phosphorylation PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
S486 Phosphorylation PhosphoSitePlus   UniProt 23186163
Site PTM Type PTM Enzyme Score Source PMID
S17 Phosphorylation HPRD 19651622, 20166139, 18578522, ...17081983
S19 Phosphorylation HPRD 19651622, 20166139, 17081983
S20 Phosphorylation HPRD 19651622, 18578522, 17081983
Y239 Phosphorylation HPRD 20068231
S243 Phosphorylation HPRD 20068231
S469 Phosphorylation HPRD 18578522
Site PTM Type PTM Enzyme Score Source PMID
S27 Phosphorylation HPRD 19651622, 20166139, 18578522, ...17081983
S29 Phosphorylation HPRD 19651622, 20166139, 17081983
S30 Phosphorylation HPRD 19651622, 18578522, 17081983
Y249 Phosphorylation HPRD 20068231
S253 Phosphorylation HPRD 20068231
S479 Phosphorylation HPRD 18578522


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S17 R17 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S27 R27 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S42 F42 Biomuta DOID:4159 / skin cancer [ cosmic ]
S469 N469 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S479 N479 Biomuta DOID:4362 / cervical cancer [ cosmic ]