iPTMnet Report for Q62432 (Smad2)
Protein Information
| UniProt AC / UniProt ID | Q62432 / SMAD2_MOUSE |
| Protein Name | Mothers against decapentaplegic homolog 2 |
| Gene Name | Name: Smad2 Synonyms:Madh2,Madr2; |
| Organism | Mus musculus (Mouse) |
| PRO ID | PR:Q62432 |
| PRO Name | mothers against decapentaplegic homolog 2 (mouse) |
| Definition | A smad2 that is encoded in the genome of mouse. |
| Short Label | mSMAD2 |
| Category | organism-gene |
DAG ViewQ62432 (Smad2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T8 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 21383698 | ||
| S47 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K54 | Acetylation | score1 | PhosphoSitePlus | |||
| Y102 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S118 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T172 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S245 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 28870245 | ||
| S250 | Phosphorylation | score0 | RLIMS-P | 28870245 | ||
| S255 | Phosphorylation | score0 | RLIMS-P | 28870245 | ||
| T324 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S433 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S458 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S465 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P | 28870245, 32535965, 21949412, ... | ||
| S467 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P | 28870245, 21949412, 27441395, ... |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Phosphorylation | score2 | PRO | 15496141 | |||
| Ubiquitination | score2 | PRO | 15496141 | |||
| S465 | Phosphorylation | PR:000025976 ((TGFBR2/iso:1/SigPep-/Phos:1)*2) | score3 | PRO | 9346966, 15496141, 8980228 | |
| S467 | Phosphorylation | PR:000025976 ((TGFBR2/iso:1/SigPep-/Phos:1)*2) | score3 | PRO | 9346966, 15496141, 8980228 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S435 | Phosphorylation | PR:000025976 ((TGFBR2/iso:1/SigPep-/Phos:1)*2) | score1 | PRO | ||
| S437 | Phosphorylation | PR:000025976 ((TGFBR2/iso:1/SigPep-/Phos:1)*2) | score1 | PRO |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000025942 (mSMAD2/iso:Long/Phos:1) | pS465,pS467 | PR:000025976 ((TGFBR2/iso:1/SigPep-/Phos:1)*2) | PRO | 8980228, 9346966 | |
| PR:000036482 (mSMAD2/iso:Long/PhosUbiq+) | ub | PRO | 15496141 | ||
| PR:000036482 (mSMAD2/iso:Long/PhosUbiq+) | p | PRO | 15496141 | ||
| PR:000036555 (mSMAD2/iso:Long/PhosUbiq:1) | ub | PRO | 15496141 | ||
| PR:000036555 (mSMAD2/iso:Long/PhosUbiq:1) | pS465,pS467 | PRO | 15496141 | ||
| PR:000025943 (mSMAD2/iso:Short/Phos:1) | pS435,pS437 | PR:000025976 ((TGFBR2/iso:1/SigPep-/Phos:1)*2) | PRO |
Proteoform PPIs
|
Protein 1 | Relation | Protein 2 | Source | PMID |
|---|---|---|---|---|---|
| PR:000025942 (mSMAD2/iso:Long/Phos:1) | Interaction | PR:P97471 (mSMAD4) | PRO | 11043574 |
