iPTMnet Report Q62432 Smad2

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q62432 / SMAD2_MOUSE
Protein Name	Mothers against decapentaplegic homolog 2
Gene Name	Name: Smad2 Synonyms:Madh2,Madr2;
Organism	Mus musculus (Mouse)

PRO ID	PR:Q62432 DAG View
PRO Name	mothers against decapentaplegic homolog 2 (mouse)
Definition	A smad2 that is encoded in the genome of mouse.
Short Label	mSMAD2
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q62432 (Smad2) as Substrate

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T8	Phosphorylation		score3	PhosphoSitePlus RLIMS-P	21383698
	S47	Phosphorylation		score1	PhosphoSitePlus
	K54	Acetylation		score1	PhosphoSitePlus
	Y102	Phosphorylation		score1	PhosphoSitePlus
	S118	Phosphorylation		score1	PhosphoSitePlus
	T172	Phosphorylation		score1	PhosphoSitePlus
	S245	Phosphorylation		score3	PhosphoSitePlus RLIMS-P	28870245
	S250	Phosphorylation		score0	RLIMS-P	28870245
	S255	Phosphorylation		score0	RLIMS-P	28870245
	T324	Phosphorylation		score1	PhosphoSitePlus
	S433	Phosphorylation		score1	PhosphoSitePlus
	S458	Phosphorylation		score1	PhosphoSitePlus
	S465	Phosphorylation		score4	PhosphoSitePlus RLIMS-P	28870245, 32535965, 21949412, ...27441395, 23527246, 29620144, 29203869, 21731500
	S467	Phosphorylation		score4	PhosphoSitePlus RLIMS-P	28870245, 21949412, 27441395, ...23527246, 29620144, 29203869, 21731500

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
		Phosphorylation		score2	PRO	15496141
		Ubiquitination		score2	PRO	15496141
	S465	Phosphorylation		score3	PRO	9346966, 15496141, 8980228
	S465	Phosphorylation	PR:000025976 ((TGFBR2/iso:1/SigPep-/Phos:1)*2)	score3	PRO	9346966, 8980228
	S467	Phosphorylation		score3	PRO	9346966, 15496141, 8980228
	S467	Phosphorylation	PR:000025976 ((TGFBR2/iso:1/SigPep-/Phos:1)*2)	score3	PRO	9346966, 8980228

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S435	Phosphorylation		score1	PRO
	S435	Phosphorylation	PR:000025976 ((TGFBR2/iso:1/SigPep-/Phos:1)*2)	score1	PRO
	S437	Phosphorylation		score1	PRO
	S437	Phosphorylation	PR:000025976 ((TGFBR2/iso:1/SigPep-/Phos:1)*2)	score1	PRO

Proteoforms

	PRO ID (Short Label)	Sites	PTM Enzyme	Source	PMID
	PR:000025942 (mSMAD2/iso:Long/Phos:1)	pS465,pS467	PR:000025976 ((TGFBR2/iso:1/SigPep-/Phos:1)*2)	PRO	8980228, 9346966
	PR:000036482 (mSMAD2/iso:Long/PhosUbiq+)	ub		PRO	15496141
	PR:000036482 (mSMAD2/iso:Long/PhosUbiq+)	p		PRO	15496141
	PR:000036555 (mSMAD2/iso:Long/PhosUbiq:1)	ub		PRO	15496141
	PR:000036555 (mSMAD2/iso:Long/PhosUbiq:1)	pS465,pS467		PRO	15496141
	PR:000025943 (mSMAD2/iso:Short/Phos:1)	pS435,pS437	PR:000025976 ((TGFBR2/iso:1/SigPep-/Phos:1)*2)	PRO

Proteoform PPIs

	Protein 1	Relation	Protein 2	Source	PMID
	PR:000025942 (mSMAD2/iso:Long/Phos:1)	Interaction	PR:P97471 (mSMAD4)	PRO	11043574