iPTMnet Report for Q5VSY0 (GKAP1)
Protein Information
UniProt AC / UniProt ID | Q5VSY0 / GKAP1_HUMAN |
Protein Name | G kinase-anchoring protein 1 |
Gene Name | Name: GKAP1 Synonyms:GKAP42;ORFNames:FKSG21; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q5VSY0 |
PRO Name | G kinase-anchoring protein 1 (human) |
Definition | A G kinase-anchoring protein 1 that is encoded in the genome of human. |
Short Label | hGKAP1 |
Category | organism-gene |
Q5VSY0 (GKAP1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
S8 | Phosphorylation | score1 | PhosphoSitePlus | |||
T12 | Phosphorylation | score1 | PhosphoSitePlus | |||
S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
S25 | Phosphorylation | score1 | PhosphoSitePlus | |||
S27 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 23186163, 20068231 | ||
S29 | Phosphorylation | score1 | PhosphoSitePlus | |||
T39 | Phosphorylation | score1 | PhosphoSitePlus | |||
S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
T44 | Phosphorylation | score1 | PhosphoSitePlus | |||
K58 | Acetylation | score1 | PhosphoSitePlus | |||
K79 | Ubiquitination | score1 | PhosphoSitePlus | |||
K104 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y141 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y148 | Phosphorylation | score1 | PhosphoSitePlus | |||
T156 | Phosphorylation | score1 | PhosphoSitePlus | |||
S158 | Phosphorylation | score1 | PhosphoSitePlus | |||
T178 | O-Glycosylation | score1 | GlyGen | 21740066 | ||
S180 | O-Glycosylation | score1 | GlyGen | 21740066 | ||
K219 | Ubiquitination | score1 | PhosphoSitePlus | |||
K259 | Ubiquitination | score1 | PhosphoSitePlus | |||
K271 | Ubiquitination | score1 | PhosphoSitePlus | |||
K282 | Ubiquitination | score1 | PhosphoSitePlus | |||
K295 | Acetylation | score1 | PhosphoSitePlus | |||
K303 | Acetylation | score1 | PhosphoSitePlus | |||
T323 | Phosphorylation | score1 | PhosphoSitePlus | |||
T327 | Phosphorylation | score1 | PhosphoSitePlus | |||
S328 | Phosphorylation | score1 | PhosphoSitePlus | |||
S360 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S23 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S25 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S27 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
T39 | Phosphorylation | score0 | HPRD | 18077418 | ||
S42 | Phosphorylation | score0 | HPRD | 18077418 | ||
T44 | Phosphorylation | score0 | HPRD | 18077418 | ||
T50 | Phosphorylation | score0 | HPRD | 18077418 | ||
S106 | Phosphorylation | Q13976 (PRKG1) | score1 | HPRD | 10671526 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S8 | Y8 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S25 | R25 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
T50 | I50 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T178 | A178 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
T323 | A323 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S328 | L328 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |