iPTMnet Report for Q5VSY0 (GKAP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q5VSY0 / GKAP1_HUMAN
Protein Name G kinase-anchoring protein 1
Gene Name Name: GKAP1
Synonyms:GKAP42;ORFNames:FKSG21;
Organism Homo sapiens (Human)

PRO ID PR:Q5VSY0
DAG View
PRO Name G kinase-anchoring protein 1 (human)
Definition A G kinase-anchoring protein 1 that is encoded in the genome of human.
Short Label hGKAP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q5VSY0 (GKAP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S8 Phosphorylation PhosphoSitePlus
T12 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S29 Phosphorylation PhosphoSitePlus
T39 Phosphorylation PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
T44 Phosphorylation PhosphoSitePlus
K58 Acetylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
Y141 Phosphorylation PhosphoSitePlus
Y148 Phosphorylation PhosphoSitePlus
T156 Phosphorylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
T178 O-Glycosylation GlyGen 21740066
S180 O-Glycosylation GlyGen 21740066
K219 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
K295 Acetylation PhosphoSitePlus
K303 Acetylation PhosphoSitePlus
T323 Phosphorylation PhosphoSitePlus
T327 Phosphorylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation HPRD 18669648, 20068231
S25 Phosphorylation HPRD 18669648, 20068231
S27 Phosphorylation HPRD 18669648, 20068231
T39 Phosphorylation HPRD 18077418
S42 Phosphorylation HPRD 18077418
T44 Phosphorylation HPRD 18077418
T50 Phosphorylation HPRD 18077418
S106 Phosphorylation HPRD 10671526
S106 Phosphorylation Q13976 (PRKG1) HPRD 10671526


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S8 Y8 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S25 R25 Biomuta DOID:1612 / breast cancer [ cosmic ]
T50 I50 Biomuta DOID:4159 / skin cancer [ cosmic ]
T178 A178 Biomuta DOID:1319 / brain cancer [ icgc ]
T323 A323 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S328 L328 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]