iPTMnet Report for Q5SW96 (LDLRAP1)
Protein Information
| UniProt AC / UniProt ID | Q5SW96 / ARH_HUMAN |
| Protein Name | Low density lipoprotein receptor adapter protein 1 |
| Gene Name | Name: LDLRAP1 Synonyms:ARH; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q5SW96 |
| PRO Name | low density lipoprotein receptor adapter protein 1 (human) |
| Definition | A low density lipoprotein receptor adapter protein 1 that is encoded in the genome of human. |
| Short Label | hLDLRAP1 |
| Category | organism-gene |
Q5SW96 (LDLRAP1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 22814378 | ||
| K5 | Methylation | score1 | PhosphoSitePlus | |||
| K5 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S14 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 18669648, 21778424, 23186163 | ||
| S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K19 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S67 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K79 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S93 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K184 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S186 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 17525332, 23186163 | ||
| S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T274 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T277 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y283 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S288 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K5 | M5 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S67 | L67 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| K72 | N72 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |
DAG View