iPTMnet Report for Q5SW96 (LDLRAP1)
Protein Information
UniProt AC / UniProt ID | Q5SW96 / ARH_HUMAN |
Protein Name | Low density lipoprotein receptor adapter protein 1 |
Gene Name | Name: LDLRAP1 Synonyms:ARH; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q5SW96 |
PRO Name | low density lipoprotein receptor adapter protein 1 (human) |
Definition | A low density lipoprotein receptor adapter protein 1 that is encoded in the genome of human. |
Short Label | hLDLRAP1 |
Category | organism-gene |
Q5SW96 (LDLRAP1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22814378 | ||
K5 | Methylation | score1 | PhosphoSitePlus | |||
K5 | Ubiquitination | score1 | PhosphoSitePlus | |||
S14 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 18669648, 21778424, 23186163 | ||
S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
K19 | Ubiquitination | score1 | PhosphoSitePlus | |||
S67 | Phosphorylation | score1 | PhosphoSitePlus | |||
K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
K79 | Ubiquitination | score1 | PhosphoSitePlus | |||
S93 | Phosphorylation | score1 | PhosphoSitePlus | |||
K184 | Ubiquitination | score1 | PhosphoSitePlus | |||
S186 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 17525332, 23186163 | ||
S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
T274 | Phosphorylation | score1 | PhosphoSitePlus | |||
T277 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y283 | Phosphorylation | score1 | PhosphoSitePlus | |||
S288 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K5 | M5 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S67 | L67 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
K72 | N72 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |