iPTMnet Report for Q460N3 (PARP15)
Protein Information
| UniProt AC / UniProt ID | Q460N3 / PAR15_HUMAN |
| Protein Name | Protein mono-ADP-ribosyltransferase PARP15 |
| Gene Name | Name: PARP15 Synonyms:BAL3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q460N3 |
| PRO Name | protein mono-ADP-ribosyltransferase PARP15 (human) |
| Definition | A protein mono-ADP-ribosyltransferase PARP15 that is encoded in the genome of human. |
| Short Label | hPARP15 |
| Category | organism-gene |
Q460N3 (PARP15) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S63 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K128 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K273 | Acetylation | score1 | PhosphoSitePlus | |||
| K291 | Acetylation | score1 | PhosphoSitePlus | |||
| C293 | Methylation | score1 | IEDB | 31844290 | ||
| C369 | Methylation | score1 | IEDB | 31844290 | ||
| K386 | Ubiquitination | score1 | PhosphoSitePlus | |||
| F513 | Methylation | score1 | IEDB | 32357974 | ||
| T516 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S518 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S519 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y520 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K581 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T634 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K638 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S63 | P63 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| K273 | T273 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| C369 | Y369 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| C369 | F369 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S519 | F519 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T634 | P634 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
| T634 | I634 | Biomuta | DOID:10534 / stomach cancer [ icgc ] | |
| K638 | N638 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View