iPTMnet Report for Q460N3 (PARP15)
Protein Information
UniProt AC / UniProt ID | Q460N3 / PAR15_HUMAN |
Protein Name | Protein mono-ADP-ribosyltransferase PARP15 |
Gene Name | Name: PARP15 Synonyms:BAL3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q460N3 |
PRO Name | protein mono-ADP-ribosyltransferase PARP15 (human) |
Definition | A protein mono-ADP-ribosyltransferase PARP15 that is encoded in the genome of human. |
Short Label | hPARP15 |
Category | organism-gene |
Q460N3 (PARP15) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S63 | Phosphorylation | score1 | PhosphoSitePlus | |||
K128 | Ubiquitination | score1 | PhosphoSitePlus | |||
K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
K273 | Acetylation | score1 | PhosphoSitePlus | |||
K291 | Acetylation | score1 | PhosphoSitePlus | |||
C293 | Methylation | score1 | IEDB | 31844290 | ||
C369 | Methylation | score1 | IEDB | 31844290 | ||
K386 | Ubiquitination | score1 | PhosphoSitePlus | |||
F513 | Methylation | score1 | IEDB | 32357974 | ||
T516 | Phosphorylation | score1 | PhosphoSitePlus | |||
S518 | Phosphorylation | score1 | PhosphoSitePlus | |||
S519 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y520 | Phosphorylation | score1 | PhosphoSitePlus | |||
K581 | Ubiquitination | score1 | PhosphoSitePlus | |||
T634 | Phosphorylation | score1 | PhosphoSitePlus | |||
K638 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S63 | P63 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
K273 | T273 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
C369 | Y369 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
C369 | F369 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S519 | F519 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
T634 | P634 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
T634 | I634 | Biomuta | DOID:10534 / stomach cancer [ icgc ] | |
K638 | N638 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |