iPTMnet Report for Q16851 (UGP2)
Protein Information
UniProt AC / UniProt ID | Q16851 / UGPA_HUMAN |
Protein Name | UTP--glucose-1-phosphate uridylyltransferase |
Gene Name | Name: UGP2 Synonyms:UGP1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q16851 |
PRO Name | UTP--glucose-1-phosphate uridylyltransferase (human) |
Definition | A UTP--glucose-1-phosphate uridylyltransferase that is encoded in the genome of human. |
Short Label | hUGP2 |
Category | organism-gene |
Q16851 (UGP2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 21406692, 22814378, 22223895, ... | ||
S2 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 20068231 | ||
R3 | Methylation | score1 | PhosphoSitePlus | |||
K10 | Ubiquitination | score1 | PhosphoSitePlus | |||
S13 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163, 24275569 | ||
K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
K52 | Acetylation | score1 | PhosphoSitePlus | |||
K52 | Ubiquitination | score1 | PhosphoSitePlus | |||
K69 | Acetylation | score1 | PhosphoSitePlus | |||
K69 | Ubiquitination | score1 | PhosphoSitePlus | |||
S72 | Phosphorylation | score1 | PhosphoSitePlus | |||
K77 | Ubiquitination | score1 | PhosphoSitePlus | |||
S85 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y89 | Phosphorylation | score1 | PhosphoSitePlus | |||
K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
S103 | Phosphorylation | score1 | PhosphoSitePlus | |||
K124 | Acetylation | score1 | PhosphoSitePlus | |||
K172 | Acetylation | score1 | PhosphoSitePlus | |||
K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y186 | Phosphorylation | score1 | PhosphoSitePlus | |||
K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
K291 | Ubiquitination | score1 | PhosphoSitePlus | |||
T296 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y298 | Phosphorylation | score1 | PhosphoSitePlus | |||
K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
K312 | Ubiquitination | score1 | PhosphoSitePlus | |||
K319 | Acetylation | score1 | PhosphoSitePlus | |||
K319 | Ubiquitination | score1 | PhosphoSitePlus | |||
T329 | Phosphorylation | score1 | PhosphoSitePlus | |||
S378 | Phosphorylation | score1 | PhosphoSitePlus | |||
T398 | Phosphorylation | score1 | PhosphoSitePlus | |||
S410 | Phosphorylation | score1 | PhosphoSitePlus | |||
S419 | Phosphorylation | score1 | PhosphoSitePlus | |||
K421 | Ubiquitination | score1 | PhosphoSitePlus | |||
T426 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S434 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S435 | Phosphorylation | score1 | PhosphoSitePlus | |||
T437 | Phosphorylation | score1 | PhosphoSitePlus | |||
K438 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
Y442 | Phosphorylation | score1 | PhosphoSitePlus | |||
S448 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
T459 | Phosphorylation | score1 | PhosphoSitePlus | |||
S461 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R3 | T3 | Biomuta | DOID:3571 / liver cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic, icgc ] | |
K69 | R69 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S85 | L85 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S103 | F103 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] | |
K198 | E198 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S410 | C410 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
S434 | N434 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
S435 | Y435 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:4606 / bile duct cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
T437 | M437 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T437 | R437 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T459 | K459 | Biomuta | DOID:184 / bone cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |