iPTMnet Report for Q16851 (UGP2)
Protein Information
| UniProt AC / UniProt ID | Q16851 / UGPA_HUMAN |
| Protein Name | UTP--glucose-1-phosphate uridylyltransferase |
| Gene Name | Name: UGP2 Synonyms:UGP1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q16851 |
| PRO Name | UTP--glucose-1-phosphate uridylyltransferase (human) |
| Definition | A UTP--glucose-1-phosphate uridylyltransferase that is encoded in the genome of human. |
| Short Label | hUGP2 |
| Category | organism-gene |
Q16851 (UGP2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S2 | Acetylation | score1 | UniProt | 21406692, 22814378, 22223895, ... | ||
| S2 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 20068231 | ||
| R3 | Methylation | score1 | PhosphoSitePlus | |||
| K10 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S13 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163, 24275569 | ||
| K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K52 | Acetylation | score1 | PhosphoSitePlus | |||
| K52 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K69 | Acetylation | score1 | PhosphoSitePlus | |||
| K69 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S72 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K77 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S85 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y89 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S103 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K124 | Acetylation | score1 | PhosphoSitePlus | |||
| K172 | Acetylation | score1 | PhosphoSitePlus | |||
| K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y186 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K291 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T296 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y298 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K312 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K319 | Acetylation | score1 | PhosphoSitePlus | |||
| K319 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T329 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S378 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T398 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S410 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S419 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K421 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T426 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S434 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S435 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T437 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K438 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| Y442 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S448 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| T459 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S461 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R3 | T3 | Biomuta | DOID:3571 / liver cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic, icgc ] | |
| K69 | R69 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S85 | L85 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S103 | F103 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] | |
| K198 | E198 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S410 | C410 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
| S434 | N434 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| S435 | Y435 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:4606 / bile duct cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
| T437 | M437 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T437 | R437 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T459 | K459 | Biomuta | DOID:184 / bone cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
DAG View