Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16719 / KYNU_HUMAN
Protein Name Kynureninase
Gene Name Name: KYNU
Organism Homo sapiens (Human)

PRO ID PR:Q16719
DAG View
PRO Name kynureninase (human)
Definition A kynureninase that is encoded in the genome of human.
Short Label hKYNU
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16719 (KYNU) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S4 Phosphorylation PhosphoSitePlus
S5 Phosphorylation PhosphoSitePlus
T12 Phosphorylation PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
Y100 Phosphorylation PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
T111 Phosphorylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus
K420 Ubiquitination PhosphoSitePlus
K427 Ubiquitination PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
T463 Phosphorylation PhosphoSitePlus
K464 Acetylation PhosphoSitePlus
K464 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation HPRD 20068231
T111 Phosphorylation HPRD 20068231
S115 Phosphorylation HPRD 20068231
T297 Phosphorylation HPRD 20068231
T365 Phosphorylation HPRD 20068231
S460 Phosphorylation HPRD 20068231
T463 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation HPRD 20068231
T111 Phosphorylation HPRD 20068231
S115 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T12 R12 Biomuta DOID:1324 / lung cancer [ tcga ]
K64 E64 Biomuta DOID:263 / kidney cancer [ tcga ]
K121 N121 Biomuta DOID:363 / uterine cancer [ tcga ]
K157 N157 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]