iPTMnet Report for Q16288 (NTRK3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q16288 / NTRK3_HUMAN
Protein Name NT-3 growth factor receptor precursor
Gene Name Name: NTRK3
Synonyms:TRKC;
Organism Homo sapiens (Human)

PRO ID PR:Q16288
DAG View
PRO Name NT-3 growth factor receptor (human)
Definition An NT-3 growth factor receptor that is encoded in the genome of human.
Short Label hNTRK3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q16288 (NTRK3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y131 Phosphorylation PhosphoSitePlus
T220 Phosphorylation PhosphoSitePlus
T386 Phosphorylation PhosphoSitePlus
Y516 Phosphorylation Q16288 (NTRK3) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 11877382, 26216473, 25196463
Y558 Phosphorylation PhosphoSitePlus
S701 Phosphorylation PhosphoSitePlus
Y705 Phosphorylation PhosphoSitePlus
Y709 Phosphorylation IntAct   PhosphoSitePlus 12237455
Y710 Phosphorylation PhosphoSitePlus
Y800 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y597 Phosphorylation PhosphoSitePlus
Y604 Phosphorylation PhosphoSitePlus
S606 Phosphorylation PhosphoSitePlus


Q16288 (NTRK3) as PTM Enzyme



Substrate Site Score Source PMID
Q16288 (NTRK3) Y516 UniProt 25196463


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y516 H516 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y558 C558 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S701 F701 Biomuta DOID:4159 / skin cancer [ cosmic ]
S701 T701 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
Y705 H705 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y705 N705 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
Y709 F709 Biomuta [ cosmic ]
Y710 H710 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y800 H800 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y800 C800 Biomuta DOID:10534 / stomach cancer [ cosmic ]