iPTMnet Report for Q15904 (ATP6AP1)
Protein Information
| UniProt AC / UniProt ID | Q15904 / VAS1_HUMAN |
| Protein Name | V-type proton ATPase subunit S1 precursor |
| Gene Name | Name: ATP6AP1 Synonyms:ATP6IP1,ATP6S1,VATPS1,XAP3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q15904 |
| PRO Name | V-type proton ATPase subunit S1 (human) |
| Definition | A V-type proton ATPase subunit S1 that is encoded in the genome of human. |
| Short Label | hATP6AP1 |
| Category | organism-gene |
DAG ViewQ15904 (ATP6AP1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T7 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 16565220 | ||
| N170 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
| S172 | O-Glycosylation | score1 | GlyGen | 32119511, 34019948, 34725712, ... | ||
| T184 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| K211 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T218 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N261 | N-Glycosylation | score4 | GlyGen UniProt | 33065002, 19159218, 24190977 | ||
| N273 | N-Glycosylation | score4 | GlyGen UniProt | 33065002, 19159218, 29741879 | ||
| T286 | Phosphorylation | score1 | IEDB | 35494241 | ||
| N296 | N-Glycosylation | score3 | GlyGen UniProt | 33065002 | ||
| N303 | N-Glycosylation | score3 | GlyGen UniProt | 33065002 | ||
| T319 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T320 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R330 | Methylation | score1 | PhosphoSitePlus | |||
| N350 | N-Glycosylation | score3 | GlyGen UniProt | 33065002 | ||
| N357 | N-Glycosylation | score3 | GlyGen UniProt | 33065002 | ||
| K380 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C418 | Methylation | score1 | IEDB | 31844290 | ||
| K460 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S465 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K211 | E211 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| N296 | S296 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| R330 | C330 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:2394 / ovarian cancer [ cosmic ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
| R330 | P330 | Biomuta | [ cosmic ] DOID:1115 / sarcoma [ icgc ] | |
| C418 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| S465 | F465 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S465 | Y465 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
