Protein Information

Cytoscape View

UniProt AC / UniProt ID Q15904 / VAS1_HUMAN
Protein Name V-type proton ATPase subunit S1 precursor
Gene Name Name: ATP6AP1
Organism Homo sapiens (Human)

PRO ID PR:Q15904
DAG View
PRO Name V-type proton ATPase subunit S1 (human)
Definition A V-type proton ATPase subunit S1 that is encoded in the genome of human.
Short Label hATP6AP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q15904 (ATP6AP1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
T7 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 16565220
N170 N-Glycosylation GlyGen 23090970, 29741879, 24190977
T184 O-Glycosylation PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
T218 Phosphorylation PhosphoSitePlus
N261 N-Glycosylation GlyGen   UniProt 19159218, 24190977
N273 N-Glycosylation GlyGen   UniProt 29741879, 19159218
T319 Phosphorylation PhosphoSitePlus
T320 Phosphorylation PhosphoSitePlus
R330 Methylation PhosphoSitePlus
K380 Ubiquitination PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus   UniProt 23186163

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K211 E211 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
R330 P330 Biomuta DOID:1115 / sarcoma [ tcga ]
R330 C330 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
S465 F465 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S465 Y465 Biomuta DOID:363 / uterine cancer [ tcga ]