iPTMnet Report for Q15366 (PCBP2)
Protein Information
UniProt AC / UniProt ID | Q15366 / PCBP2_HUMAN |
Protein Name | Poly(rC)-binding protein 2 |
Gene Name | Name: PCBP2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q15366 |
PRO Name | poly(rC)-binding protein 2 (human) |
Definition | A poly(rC)-binding protein 2 that is encoded in the genome of human. |
Short Label | hPCBP2 |
Category | organism-gene |
Q15366 (PCBP2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T15 | Phosphorylation | score1 | PhosphoSitePlus | |||
K23 | Acetylation | score1 | PhosphoSitePlus | |||
K23 | Sumoylation | score1 | PhosphoSitePlus | |||
K23 | Ubiquitination | score1 | PhosphoSitePlus | |||
S27 | Phosphorylation | score1 | PhosphoSitePlus | |||
K31 | Acetylation | score1 | PhosphoSitePlus | |||
K31 | Sumoylation | score1 | PhosphoSitePlus | |||
K31 | Ubiquitination | score1 | PhosphoSitePlus | |||
S50 | Phosphorylation | score1 | PhosphoSitePlus | |||
C54 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
T65 | Phosphorylation | score1 | PhosphoSitePlus | |||
K70 | Acetylation | score1 | PhosphoSitePlus | |||
T99 | Phosphorylation | score1 | PhosphoSitePlus | |||
S107 | Phosphorylation | score1 | PhosphoSitePlus | |||
C109 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
S111 | Phosphorylation | score1 | PhosphoSitePlus | |||
K115 | Sumoylation | score1 | PhosphoSitePlus | |||
K115 | Ubiquitination | score1 | PhosphoSitePlus | |||
K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
S154 | Phosphorylation | score1 | PhosphoSitePlus | |||
C158 | Methylation | score1 | IEDB | 31844290 | ||
C158 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
K160 | Ubiquitination | score1 | PhosphoSitePlus | |||
C163 | Methylation | score1 | IEDB | 31844290 | ||
S173 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus RLIMS-P+ Signor UniProt | 21406692, 23186163, 17081983, ... | ||
S173 | Phosphorylation | P11274 (BCR) | score2 | RLIMS-P+ | 17475908 | |
S173 | Phosphorylation | P27361 (MAPK3) | score3 | RLIMS-P+ Signor | 17475908 | |
S173 | Phosphorylation | P28482 (MAPK1) | score3 | RLIMS-P+ Signor | 17475908 | |
T179 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y182 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
K185 | Acetylation | score1 | PhosphoSitePlus | |||
K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
S187 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S188 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S189 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus RLIMS-P+ Signor UniProt | 17081983, 17475908, 18669648, ... | ||
S189 | Phosphorylation | P11274 (BCR) | score2 | RLIMS-P+ | 17475908 | |
S189 | Phosphorylation | P27361 (MAPK3) | score3 | RLIMS-P+ Signor | 17475908 | |
S189 | Phosphorylation | P28482 (MAPK1) | score3 | RLIMS-P+ Signor | 17475908 | |
T202 | Phosphorylation | score1 | PhosphoSitePlus | |||
T213 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P+ Signor | 17475908 | ||
T213 | Phosphorylation | P11274 (BCR) | score2 | RLIMS-P+ | 17475908 | |
T213 | Phosphorylation | P27361 (MAPK3) | score3 | RLIMS-P+ Signor | 17475908 | |
T213 | Phosphorylation | P28482 (MAPK1) | score3 | RLIMS-P+ Signor | 17475908 | |
Y230 | Phosphorylation | score1 | PhosphoSitePlus | |||
T231 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y236 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 16094384 | ||
K245 | Ubiquitination | score1 | PhosphoSitePlus | |||
S266 | Phosphorylation | score1 | PhosphoSitePlus | |||
S270 | Phosphorylation | score1 | PhosphoSitePlus | |||
S271 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S272 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus RLIMS-P+ Signor UniProt | 17475908, 18669648 | ||
S272 | Phosphorylation | P11274 (BCR) | score2 | RLIMS-P+ | 17475908 | |
S272 | Phosphorylation | P27361 (MAPK3) | score3 | RLIMS-P+ Signor | 17475908 | |
S272 | Phosphorylation | P28482 (MAPK1) | score3 | RLIMS-P+ Signor | 17475908 | |
K276 | Sumoylation | score1 | PhosphoSitePlus | |||
Y278 | Phosphorylation | score1 | PhosphoSitePlus | |||
S284 | O-Glycosylation | score1 | GlyGen | 28604694 | ||
S289 | Phosphorylation | score1 | PhosphoSitePlus | |||
K309 | Acetylation | score1 | PhosphoSitePlus | |||
K309 | Sumoylation | score1 | PhosphoSitePlus | |||
K309 | Ubiquitination | score1 | PhosphoSitePlus | |||
R314 | Methylation | score1 | PhosphoSitePlus | |||
K322 | Sumoylation | score1 | PhosphoSitePlus | |||
K322 | Ubiquitination | score1 | PhosphoSitePlus | |||
S340 | Phosphorylation | score1 | PhosphoSitePlus | |||
S364 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 20068231 | ||
S365 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T13 | Phosphorylation | score0 | HPRD | 20068231 | ||
T15 | Phosphorylation | score0 | HPRD | 20068231 | ||
T169 | Phosphorylation | score0 | HPRD | 20068231 | ||
S171 | Phosphorylation | score0 | HPRD | 20068231 | ||
S173 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 19007248, ... | ||
Y182 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 20068231 | ||
S187 | Phosphorylation | score0 | HPRD | 18691976, 20230923, 19651622, ... | ||
S188 | Phosphorylation | score0 | HPRD | 18691976, 17081983, 20230923, ... | ||
S189 | Phosphorylation | score0 | HPRD | 18691976, 17081983, 20230923, ... | ||
Y236 | Phosphorylation | score0 | HPRD | 16094384 | ||
S271 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S272 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18669648, 20068231, 17924679 | ||
K276 | Sumoylation | score1 | PhosphoSitePlus | |||
K276 | Ubiquitination | score1 | PhosphoSitePlus | |||
S365 | Phosphorylation | score0 | HPRD | 19651622, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T13 | Phosphorylation | score0 | HPRD | 20068231 | ||
T15 | Phosphorylation | score0 | HPRD | 20068231 | ||
S169 | Phosphorylation | score0 | HPRD | 20068231 | ||
Y178 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 20068231 | ||
S183 | Phosphorylation | score0 | HPRD | 18691976, 20230923, 19651622, ... | ||
S184 | Phosphorylation | score0 | HPRD | 18691976, 17081983, 20230923, ... | ||
S185 | Phosphorylation | score0 | HPRD | 18691976, 17081983, 20230923, ... | ||
Y232 | Phosphorylation | score0 | HPRD | 16094384 | ||
S267 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S268 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 17924679 | ||
S361 | Phosphorylation | score0 | HPRD | 19651622, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T13 | Phosphorylation | score0 | HPRD | 20068231 | ||
T15 | Phosphorylation | score0 | HPRD | 20068231 | ||
S169 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
K172 | Ubiquitination | score1 | PhosphoSitePlus | |||
T175 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
S184 | Phosphorylation | score1 | PhosphoSitePlus | |||
S185 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y195 | Phosphorylation | score1 | PhosphoSitePlus | |||
T196 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y201 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 16094384 | ||
T209 | Phosphorylation | score1 | PhosphoSitePlus | |||
S236 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S237 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18669648, 20068231, 17924679 | ||
K241 | Sumoylation | score1 | PhosphoSitePlus | |||
K241 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y243 | Phosphorylation | score1 | PhosphoSitePlus | |||
S330 | Phosphorylation | score0 | HPRD | 19651622, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T179 | Phosphorylation | score1 | PhosphoSitePlus | |||
K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
S188 | Phosphorylation | score1 | PhosphoSitePlus | |||
S189 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y199 | Phosphorylation | score1 | PhosphoSitePlus | |||
T200 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y205 | Phosphorylation | score1 | PhosphoSitePlus | |||
T213 | Phosphorylation | score1 | PhosphoSitePlus | |||
S241 | Phosphorylation | score1 | PhosphoSitePlus | |||
K245 | Sumoylation | score1 | PhosphoSitePlus | |||
K245 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y247 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C109 | Y109 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
S154 | F154 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S236 | R236 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
K245 | M245 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S267 | R267 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S270 | T270 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S271 | R271 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S289 | Y289 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
R314 | C314 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
R314 | H314 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
R314 | S314 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S340 | T340 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |