Protein Information

Cytoscape View


UniProt AC / UniProt ID Q15349 / KS6A2_HUMAN
Protein Name Ribosomal protein S6 kinase alpha-2
Gene Name Name: RPS6KA2
Synonyms:MAPKAPK1C,RSK3;
Organism Homo sapiens (Human)

PRO ID PR:Q15349
DAG View
PRO Name ribosomal protein S6 kinase alpha-2 (human)
Definition A ribosomal protein S6 kinase alpha-2 that is encoded in the genome of human.
Short Label hRPS6KA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q15349 (RPS6KA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
K91 Acetylation PhosphoSitePlus
K94 Acetylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
Y135 Phosphorylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
Y217 Phosphorylation PhosphoSitePlus
S218 Phosphorylation O15530 (PDPK1) , Q15349 (RPS6KA2) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   UniProt 10480933, 7642538, 17192257
T222 Phosphorylation PhosphoSitePlus
K295 Acetylation PhosphoSitePlus
T356 Phosphorylation PRO
S360 Phosphorylation PRO
S377 Phosphorylation PRO   PhosphoSitePlus   UniProt 19369195
S381 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
Y426 Phosphorylation PhosphoSitePlus
K430 Ubiquitination PhosphoSitePlus
K450 Ubiquitination PhosphoSitePlus
Y463 Phosphorylation PhosphoSitePlus
T471 Phosphorylation PhosphoSitePlus
K473 Ubiquitination PhosphoSitePlus
S546 Phosphorylation PhosphoSitePlus
T570 Phosphorylation Q15349 (RPS6KA2) PRO   PhosphoSitePlus 7642538
Y573 Phosphorylation PhosphoSitePlus
T574 Phosphorylation PhosphoSitePlus
T618 Phosphorylation PhosphoSitePlus
S628 Phosphorylation PhosphoSitePlus
K630 Ubiquitination PhosphoSitePlus
S650 Phosphorylation PhosphoSitePlus
T662 Phosphorylation PhosphoSitePlus
S730 Phosphorylation PRO
Site PTM Type PTM Enzyme Score Source PMID
S106 Phosphorylation HPRD 20068231
Y217 Phosphorylation HPRD 18691976
S218 Phosphorylation Q15349 (RPS6KA2) HPRD 17192257
T222 Phosphorylation Q15349 (RPS6KA2) HPRD 17192257
S377 Phosphorylation HPRD 15345747
T570 Phosphorylation HPRD 18691976


Q15349 (RPS6KA2) as PTM Enzyme



Substrate Site Score Source PMID
P16220 (CREB1) S133 HPRD   neXtProt   PhosphoSitePlus 8688081, 9528766, 11175347, ...9687510, 11698596, 9829964
P17676 (CEBPB) S321 neXtProt 20351173
P25963 (NFKBIA) S32 Signor 20385620
P32004-2 (L1CAM) S1152 HPRD 8663493
Q15349-1 (RPS6KA2) S218 HPRD   PhosphoSitePlus 7642538, 17192257
Q15349-1 (RPS6KA2) T222 HPRD 17192257
Q15349 (RPS6KA2) T570 PhosphoSitePlus 7642538
Q92934 (BAD) S75 HPRD   Signor 12897128, 10880354, 10521512, ...19282669, 9381178, 10837486
Q92934 (BAD) S118 HPRD   Signor 20166139, 18669648, 10949026, ...18707149, 10837486


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049126 (hRPS6KA2/Phos:1) pS218,pS360,pS377,pT570 PRO
PR:000049127 (hRPS6KA2/Phos:2) pS218,pT356,pS360,pS377,pT570,pS730 PRO
PR:000049128 (hRPS6KA2/Phos:3) pS360,pS377,pT570 PRO