iPTMnet Report for Q15078 (CDK5R1)
Protein Information
| UniProt AC / UniProt ID | Q15078 / CD5R1_HUMAN |
| Protein Name | Cyclin-dependent kinase 5 activator 1 precursor |
| Gene Name | Name: CDK5R1 Synonyms:CDK5R,NCK5A; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q15078 |
| PRO Name | cyclin-dependent kinase 5 activator 1 (human) |
| Definition | A cyclin-dependent kinase 5 activator 1 that is encoded in the genome of human. |
| Short Label | hCDK5R1 |
| Category | organism-gene |
DAG ViewQ15078 (CDK5R1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| G2 | Myristoylation | score1 | UniProt | 20213681 | ||
| S8 | Phosphorylation | Q00535 (CDK5) | score4 | neXtProt phospho.ELM PhosphoSitePlus Signor UniProt | 18326489, 17121855 | |
| S59 | Phosphorylation | Q05655 (PRKCD) | score2 | neXtProt | 19965374 | |
| S65 | Phosphorylation | Q05655 (PRKCD) | score2 | neXtProt | 19965374 | |
| S91 | Phosphorylation | Q9H0K1 (SIK2) | score4 | phospho.ELM PhosphoSitePlus RLIMS-P Signor | 20097924, 24561619 | |
| S124 | Phosphorylation | Q05655 (PRKCD) | score2 | neXtProt | 19965374 | |
| T138 | Phosphorylation | Q00535 (CDK5) | score4 | neXtProt phospho.ELM PhosphoSitePlus Signor UniProt | 20033852, 18326489, 17121855 | |
| Y234 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S65 | C65 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T138 | M138 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |
