iPTMnet Report Q15078 CDK5R1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q15078 / CD5R1_HUMAN
Protein Name	Cyclin-dependent kinase 5 activator 1 precursor
Gene Name	Name: CDK5R1 Synonyms:CDK5R,NCK5A;
Organism	Homo sapiens (Human)

PRO ID	PR:Q15078 DAG View
PRO Name	cyclin-dependent kinase 5 activator 1 (human)
Definition	A cyclin-dependent kinase 5 activator 1 that is encoded in the genome of human.
Short Label	hCDK5R1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q15078 (CDK5R1) as Substrate

Q15078

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	G2	Myristoylation		score1	UniProt	20213681
	S8	Phosphorylation		score4	neXtProt phospho.ELM PhosphoSitePlus Signor UniProt	18326489, 17121855
	S8	Phosphorylation	Q00535 (CDK5)	score4	neXtProt phospho.ELM PhosphoSitePlus Signor	18326489, 17121855
	S59	Phosphorylation		score2	neXtProt	19965374
	S59	Phosphorylation	Q05655 (PRKCD)	score2	neXtProt	19965374
	S65	Phosphorylation		score2	neXtProt	19965374
	S65	Phosphorylation	Q05655 (PRKCD)	score2	neXtProt	19965374
	S91	Phosphorylation		score4	phospho.ELM PhosphoSitePlus RLIMS-P Signor	20097924, 24561619
	S91	Phosphorylation	Q9H0K1 (SIK2)	score3	PhosphoSitePlus Signor	24561619
	S124	Phosphorylation		score2	neXtProt	19965374
	S124	Phosphorylation	Q05655 (PRKCD)	score2	neXtProt	19965374
	T138	Phosphorylation		score4	neXtProt phospho.ELM PhosphoSitePlus Signor UniProt	20033852, 18326489, 17121855
	T138	Phosphorylation	Q00535 (CDK5)	score4	neXtProt phospho.ELM PhosphoSitePlus Signor	18326489, 17121855
	Y234	Phosphorylation		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S65	C65	Biomuta		DOID:1324 / lung cancer [ cosmic ]
T138	M138	Biomuta		DOID:9256 / colorectal cancer [ cosmic, icgc ]