iPTMnet Report for Q14534 (SQLE)
Protein Information
UniProt AC / UniProt ID | Q14534 / ERG1_HUMAN |
Protein Name | Squalene monooxygenase |
Gene Name | Name: SQLE Synonyms:ERG1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q14534 |
PRO Name | squalene monooxygenase (human) |
Definition | A squalene monooxygenase that is encoded in the genome of human. |
Short Label | hSQLE |
Category | organism-gene |
Q14534 (SQLE) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S83 | Phosphorylation | score1 | PhosphoSitePlus | |||
S83 | Ubiquitination | score1 | PhosphoSitePlus | |||
S87 | Phosphorylation | score1 | PhosphoSitePlus | |||
K90 | Ubiquitination | score1 | PhosphoSitePlus | |||
K148 | Ubiquitination | score1 | PhosphoSitePlus | |||
T150 | Phosphorylation | score1 | PhosphoSitePlus | |||
K157 | Ubiquitination | score1 | PhosphoSitePlus | |||
K235 | Ubiquitination | score1 | PhosphoSitePlus | |||
K274 | Ubiquitination | score1 | PhosphoSitePlus | |||
K290 | Ubiquitination | score1 | PhosphoSitePlus | |||
K293 | Ubiquitination | score1 | PhosphoSitePlus | |||
K312 | Ubiquitination | score1 | PhosphoSitePlus | |||
K318 | Ubiquitination | score1 | PhosphoSitePlus | |||
K363 | Ubiquitination | score1 | PhosphoSitePlus | |||
K373 | Ubiquitination | score1 | PhosphoSitePlus | |||
R413 | Methylation | score1 | PhosphoSitePlus | |||
K426 | Ubiquitination | score1 | PhosphoSitePlus | |||
K433 | Ubiquitination | score1 | PhosphoSitePlus | |||
K436 | Ubiquitination | score1 | PhosphoSitePlus | |||
K451 | Ubiquitination | score1 | PhosphoSitePlus | |||
C491 | Methylation | score1 | IEDB | 31844290 | ||
K556 | Ubiquitination | score1 | PhosphoSitePlus | |||
S559 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y566 | Phosphorylation | score1 | PhosphoSitePlus | |||
S567 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K90 | T90 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K148 | M148 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K235 | R235 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
K363 | T363 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K433 | E433 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
C491 | S491 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
S567 | A567 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |