iPTMnet Report for Q14146 (URB2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14146 / URB2_HUMAN
Protein Name Unhealthy ribosome biogenesis protein 2 homolog
Gene Name Name: URB2
Synonyms:KIAA0133;
Organism Homo sapiens (Human)

PRO ID PR:Q14146
DAG View
PRO Name unhealthy ribosome biogenesis protein 2 homolog (human)
Definition An unhealthy ribosome biogenesis protein 2 that is encoded in the genome of human.
Short Label hURB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14146 (URB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K22 Ubiquitination PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
T280 Phosphorylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
T414 Phosphorylation IEDB 35494241
K447 Acetylation PhosphoSitePlus
K447 Ubiquitination PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
Y672 Phosphorylation PhosphoSitePlus
T685 Phosphorylation PhosphoSitePlus
T689 Phosphorylation PhosphoSitePlus
S699 Phosphorylation PhosphoSitePlus
K790 Ubiquitination PhosphoSitePlus
K858 Ubiquitination PhosphoSitePlus
S908 Phosphorylation IEDB 32387766
Y913 Phosphorylation IEDB 32387766
T1027 Phosphorylation PhosphoSitePlus
S1033 Phosphorylation PhosphoSitePlus
K1034 Ubiquitination PhosphoSitePlus
K1072 Acetylation PhosphoSitePlus
K1072 Ubiquitination PhosphoSitePlus
S1140 Phosphorylation PhosphoSitePlus
S1143 Phosphorylation PhosphoSitePlus
K1195 Ubiquitination PhosphoSitePlus
R1207 Methylation PhosphoSitePlus
K1286 Ubiquitination PhosphoSitePlus
K1387 Ubiquitination PhosphoSitePlus
K1412 Ubiquitination PhosphoSitePlus
K1423 Ubiquitination PhosphoSitePlus
K1502 Ubiquitination PhosphoSitePlus
K1510 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T280 I280 Biomuta DOID:4159 / skin cancer [ cosmic ]
K336 N336 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K858 E858 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
S908 I908 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S908 C908 Biomuta DOID:3571 / liver cancer [ cosmic, icgc, tcga ] DOID:1324 / lung cancer [ cosmic ]
T1027 S1027 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T1027 A1027 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1510 N1510 Biomuta DOID:363 / uterine cancer [ cosmic ]