Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14146 / URB2_HUMAN
Protein Name Unhealthy ribosome biogenesis protein 2 homolog
Gene Name Name: URB2
Synonyms:KIAA0133;
Organism Homo sapiens (Human)

PRO ID PR:Q14146
DAG View
PRO Name unhealthy ribosome biogenesis protein 2 homolog (human)
Definition An unhealthy ribosome biogenesis protein 2 that is encoded in the genome of human.
Short Label hURB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14146 (URB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K22 Ubiquitination PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
T280 Phosphorylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
K447 Acetylation PhosphoSitePlus
K447 Ubiquitination PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
Y672 Phosphorylation PhosphoSitePlus
T685 Phosphorylation PhosphoSitePlus
T689 Phosphorylation PhosphoSitePlus
K790 Ubiquitination PhosphoSitePlus
K858 Ubiquitination PhosphoSitePlus
T1027 Phosphorylation PhosphoSitePlus
S1033 Phosphorylation PhosphoSitePlus
K1034 Ubiquitination PhosphoSitePlus
K1072 Acetylation PhosphoSitePlus
K1072 Ubiquitination PhosphoSitePlus
S1140 Phosphorylation PhosphoSitePlus
S1143 Phosphorylation PhosphoSitePlus
K1195 Ubiquitination PhosphoSitePlus
R1207 Methylation PhosphoSitePlus
K1286 Ubiquitination PhosphoSitePlus
K1387 Ubiquitination PhosphoSitePlus
K1412 Ubiquitination PhosphoSitePlus
K1423 Ubiquitination PhosphoSitePlus
K1502 Ubiquitination PhosphoSitePlus
K1510 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K336 N336 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K858 E858 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T1027 A1027 Biomuta DOID:1909 / melanoma [ cosmic ]
K1510 N1510 Biomuta DOID:363 / uterine cancer [ cosmic ]