iPTMnet Report for Q13951 (CBFB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13951 / PEBB_HUMAN
Protein Name Core-binding factor subunit beta
Gene Name Name: CBFB
Organism Homo sapiens (Human)

PRO ID PR:Q13951
DAG View
PRO Name core-binding factor subunit beta (human)
Definition A core-binding factor subunit beta that is encoded in the genome of human.
Short Label hCBFB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13951 (CBFB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K11 Acetylation PhosphoSitePlus
K11 Ubiquitination PhosphoSitePlus
R19 Methylation PhosphoSitePlus
C25 Methylation IEDB 31844290
C25 S-Nitrosylation dbSNO 24105792
K28 Acetylation PhosphoSitePlus
K28 Ubiquitination PhosphoSitePlus
T80 Phosphorylation PhosphoSitePlus
Y85 Phosphorylation PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
Y96 Phosphorylation PhosphoSitePlus
T150 Phosphorylation PhosphoSitePlus
S169 O-Glycosylation GlyGen 34019948, 28510447, 31373491
S169 Phosphorylation PhosphoSitePlus
A173 Phosphorylation UniProt 18669648, 17081983, 20068231
K177 Acetylation PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T150 Phosphorylation PhosphoSitePlus
S173 Phosphorylation HPRD   PhosphoSitePlus 19651622, 18669648, 17081983, ...20068231
S176 Phosphorylation HPRD   PhosphoSitePlus 20068231
K185 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K94 R94 Biomuta [ cosmic ]
K94 M94 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S169 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S176 F176 Biomuta DOID:4159 / skin cancer [ cosmic ]
K185 T185 Biomuta DOID:363 / uterine cancer [ cosmic ]