iPTMnet Report for Q13951 (CBFB)
Protein Information
UniProt AC / UniProt ID | Q13951 / PEBB_HUMAN |
Protein Name | Core-binding factor subunit beta |
Gene Name | Name: CBFB |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q13951 |
PRO Name | core-binding factor subunit beta (human) |
Definition | A core-binding factor subunit beta that is encoded in the genome of human. |
Short Label | hCBFB |
Category | organism-gene |
Q13951 (CBFB) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K11 | Acetylation | score1 | PhosphoSitePlus | |||
K11 | Ubiquitination | score1 | PhosphoSitePlus | |||
R19 | Methylation | score1 | PhosphoSitePlus | |||
C25 | Methylation | score1 | IEDB | 31844290 | ||
C25 | S-Nitrosylation | score0 | dbSNO | 24105792 | ||
K28 | Acetylation | score1 | PhosphoSitePlus | |||
K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
T80 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y85 | Phosphorylation | score1 | PhosphoSitePlus | |||
K94 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y96 | Phosphorylation | score1 | PhosphoSitePlus | |||
T150 | Phosphorylation | score1 | PhosphoSitePlus | |||
S169 | O-Glycosylation | score1 | GlyGen | 34019948, 28510447, 31373491 | ||
S169 | Phosphorylation | score1 | PhosphoSitePlus | |||
A173 | Phosphorylation | score1 | UniProt | 18669648, 17081983, 20068231 | ||
K177 | Acetylation | score1 | PhosphoSitePlus | |||
K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
K178 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T150 | Phosphorylation | score1 | PhosphoSitePlus | |||
S173 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19651622, 18669648, 17081983, ... | ||
S176 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
K185 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K94 | R94 | Biomuta | [ cosmic ] | |
K94 | M94 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S169 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S176 | F176 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K185 | T185 | Biomuta | DOID:363 / uterine cancer [ cosmic ] |