iPTMnet Report for Q13761 (RUNX3)
Protein Information
UniProt AC / UniProt ID | Q13761 / RUNX3_HUMAN |
Protein Name | Runt-related transcription factor 3 |
Gene Name | Name: RUNX3 Synonyms:AML2,CBFA3,PEBP2A3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q13761 |
PRO Name | runt-related transcription factor 3 (human) |
Definition | A runt-related transcription factor 3 that is encoded in the genome of human. |
Short Label | hRUNX3 |
Category | organism-gene |
Q13761 (RUNX3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T14 | Phosphorylation | score1 | PhosphoSitePlus | |||
S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
K94 | Acetylation | score1 | PhosphoSitePlus | |||
K94 | Ubiquitination | score1 | PhosphoSitePlus | |||
K129 | Ubiquitination | score1 | PhosphoSitePlus | |||
K148 | Ubiquitination | score1 | PhosphoSitePlus | |||
S149 | Phosphorylation | P11309 (PIM1) | score2 | PhosphoSitePlus | 18767071 | |
T151 | Phosphorylation | P11309 (PIM1) | score2 | PhosphoSitePlus | 18767071 | |
T153 | Phosphorylation | P11309 (PIM1) | score2 | PhosphoSitePlus | 18767071 | |
T155 | Phosphorylation | P11309 (PIM1) | score2 | PhosphoSitePlus | 18767071 | |
K171 | Acetylation | score1 | PhosphoSitePlus | |||
T173 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 27217562 | ||
K186 | Ubiquitination | score1 | PhosphoSitePlus | |||
K192 | Acetylation | score1 | PhosphoSitePlus | |||
K192 | Sumoylation | score1 | PhosphoSitePlus | |||
K192 | Ubiquitination | score1 | PhosphoSitePlus | |||
T209 | Phosphorylation | score1 | PhosphoSitePlus | |||
S211 | Phosphorylation | score1 | PhosphoSitePlus | |||
T212 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
T212 | Phosphorylation | score1 | PhosphoSitePlus | |||
S214 | Phosphorylation | score1 | PhosphoSitePlus | |||
R216 | Methylation | score1 | PhosphoSitePlus | |||
S220 | Phosphorylation | score1 | PhosphoSitePlus | |||
T222 | Phosphorylation | score1 | PhosphoSitePlus | |||
S227 | Phosphorylation | score1 | PhosphoSitePlus | |||
T231 | Phosphorylation | score1 | PhosphoSitePlus | |||
S237 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
S243 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18220336 | ||
S251 | Phosphorylation | score1 | PhosphoSitePlus | |||
T254 | Phosphorylation | score1 | PhosphoSitePlus | |||
S261 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
S261 | Phosphorylation | score1 | PhosphoSitePlus | |||
R262 | Methylation | score1 | PhosphoSitePlus | |||
R267 | Methylation | score1 | PhosphoSitePlus | |||
S281 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
T283 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
S285 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
S288 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
S293 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
S301 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
R302 | Methylation | score1 | PhosphoSitePlus | |||
S320 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
S328 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
S356 | Phosphorylation | P11802 (CDK4) | score4 | neXtProt PhosphoSitePlus RLIMS-P Signor | 31015486, 19351720 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S17 | F17 | Biomuta | DOID:3963 / thyroid carcinoma [ cosmic, icgc ] | |
K94 | E94 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
T173 | I173 | Biomuta | DOID:1909 / melanoma [ cosmic ] | |
R216 | Q216 | Biomuta | DOID:1319 / brain cancer [ icgc ] DOID:3070 / malignant glioma [ cosmic ] | |
S220 | G220 | Biomuta | DOID:3963 / thyroid carcinoma [ cosmic, icgc ] | |
R267 | M267 | Biomuta | DOID:1909 / melanoma [ cosmic ] | |
S285 | P285 | Biomuta | DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ] | |
S285 | L285 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc, tcga ] | |
S288 | R288 | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
R302 | L302 | Biomuta | DOID:1324 / lung cancer [ tcga ] | |
S328 | F328 | Biomuta | DOID:1909 / melanoma [ icgc, tcga ] |