iPTMnet Report for Q13621 (SLC12A1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13621 / S12A1_HUMAN
Protein Name Solute carrier family 12 member 1
Gene Name Name: SLC12A1
Synonyms:NKCC2;
Organism Homo sapiens (Human)

PRO ID PR:Q13621
DAG View
PRO Name solute carrier family 12 member 1 (human)
Definition A solute carrier family 12 member 1 that is encoded in the genome of human.
Short Label hSLC12A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13621 (SLC12A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y70 Phosphorylation PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor   UniProt 21321328
S91 Phosphorylation Q9UEW8 (STK39) Signor 21321328
T95 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 21423148, 21321328, 20091762
T95 Phosphorylation O95747 (OXSR1) PhosphoSitePlus 21423148, 21321328
T95 Phosphorylation Q9UEW8 (STK39) neXtProt   PhosphoSitePlus   Signor 21423148, 21321328, 20091762
T100 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 16275913, 21423148, 21321328, ...20091762
T100 Phosphorylation O95747 (OXSR1) PhosphoSitePlus 21423148, 21321328
T100 Phosphorylation Q9BYP7 (WNK3) neXtProt 16275913
T100 Phosphorylation Q9UEW8 (STK39) neXtProt   PhosphoSitePlus   Signor 21423148, 21321328, 20091762
T105 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 16275913, 21423148, 21321328, ...20091762
T105 Phosphorylation O95747 (OXSR1) PhosphoSitePlus 21321328
T105 Phosphorylation Q9BYP7 (WNK3) neXtProt 16275913
T105 Phosphorylation Q9UEW8 (STK39) neXtProt   PhosphoSitePlus   Signor 21423148, 21321328, 20091762
T118 Phosphorylation PhosphoSitePlus 21423148
T118 Phosphorylation O95747 (OXSR1) PhosphoSitePlus 21423148
S120 Phosphorylation PhosphoSitePlus 21423148
S120 Phosphorylation O95747 (OXSR1) PhosphoSitePlus 21423148
S122 Phosphorylation neXtProt 17341212
S122 Phosphorylation Q13131 (PRKAA1) neXtProt 17341212
S130 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 30248150, 21321328, 19176702
S130 Phosphorylation Q13131 (PRKAA1) PhosphoSitePlus 19176702
Y245 Phosphorylation PhosphoSitePlus
K722 Methylation PhosphoSitePlus
K735 Methylation PhosphoSitePlus
Y944 Phosphorylation PhosphoSitePlus
S1056 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T118 I118 Biomuta DOID:4159 / skin cancer [ cosmic ]
S120 N120 Biomuta DOID:1324 / lung cancer [ cosmic ]