iPTMnet Report for Q13610 (PWP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13610 / PWP1_HUMAN
Protein Name Periodic tryptophan protein 1 homolog
Gene Name Name: PWP1
Organism Homo sapiens (Human)

PRO ID PR:Q13610
DAG View
PRO Name periodic tryptophan protein 1 homolog (human)
Definition A periodic tryptophan protein 1 that is encoded in the genome of human.
Short Label hPWP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13610 (PWP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T21 Phosphorylation PhosphoSitePlus   UniProt 23186163
K24 Ubiquitination PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
S50 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...15302935, 18669648, 24275569, 17287340, 17487921, 19690332, 20068231
T55 Phosphorylation PhosphoSitePlus   UniProt 19690332
S57 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 15302935, ...18669648, 19690332, 20068231
S59 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S65 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17287340
R85 Methylation PhosphoSitePlus
T86 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 20068231, 16565220
Y121 Phosphorylation PhosphoSitePlus
Y129 Phosphorylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
Y138 Phosphorylation PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
Y327 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
C356 Methylation IEDB 31844290
S394 Phosphorylation PhosphoSitePlus
K408 Acetylation PhosphoSitePlus
K408 Ubiquitination PhosphoSitePlus
R419 Methylation PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
S484 Phosphorylation PhosphoSitePlus
S485 Phosphorylation PhosphoSitePlus   UniProt 23186163
S487 Phosphorylation PhosphoSitePlus
S492 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T21 Phosphorylation HPRD 19007248, 19691289
S50 Phosphorylation HPRD 19413330, 17287340, 15302935, ...19664994, 19664995, 19007248, 19651622, 18669648, 18452278, 19415658, 20068231, 19691289
T55 Phosphorylation HPRD 19413330
S57 Phosphorylation HPRD 19413330, 18669648, 15302935, ...19691289, 20068231
S59 Phosphorylation HPRD 19413330, 18669648, 17287340, ...19415658, 18452278
S65 Phosphorylation HPRD 18669648, 20068231
T86 Phosphorylation HPRD 19651622, 20068231, 16565220
S484 Phosphorylation HPRD 20068231
S485 Phosphorylation HPRD 19007248
S492 Phosphorylation HPRD 20068231
S495 Phosphorylation HPRD 20068231
T497 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C356 W356 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R419 S419 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S492 N492 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T497 I497 Biomuta DOID:363 / uterine cancer [ icgc ]