iPTMnet Report for Q13561 (DCTN2)
Protein Information
UniProt AC / UniProt ID | Q13561 / DCTN2_HUMAN |
Protein Name | Dynactin subunit 2 |
Gene Name | Name: DCTN2 Synonyms:DCTN50; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q13561 |
PRO Name | dynactin subunit 2 (human) |
Definition | A dynactin subunit 2 that is encoded in the genome of human. |
Short Label | hDCTN2 |
Category | organism-gene |
Q13561 (DCTN2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22814378 | ||
K5 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y6 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 15144186 | ||
Y54 | Phosphorylation | score1 | PhosphoSitePlus | |||
K65 | Methylation | score1 | PhosphoSitePlus | |||
K65 | Ubiquitination | score1 | PhosphoSitePlus | |||
S70 | Phosphorylation | score1 | PhosphoSitePlus | |||
R72 | Methylation | score1 | PhosphoSitePlus | |||
Y81 | Phosphorylation | score1 | PhosphoSitePlus | |||
S83 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 19690332 | ||
Y86 | Phosphorylation | score1 | PhosphoSitePlus | |||
T98 | Phosphorylation | score1 | PhosphoSitePlus | |||
K102 | Ubiquitination | score1 | PhosphoSitePlus | |||
T115 | Phosphorylation | score1 | PhosphoSitePlus | |||
K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
S127 | Phosphorylation | score1 | PhosphoSitePlus | |||
T134 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K140 | Ubiquitination | score1 | PhosphoSitePlus | |||
K146 | Acetylation | score1 | IEDB | 34357683 | ||
K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
S152 | Phosphorylation | score1 | PhosphoSitePlus | |||
K156 | Ubiquitination | score1 | PhosphoSitePlus | |||
K175 | Ubiquitination | score1 | PhosphoSitePlus | |||
T198 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S202 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y207 | Phosphorylation | score1 | PhosphoSitePlus | |||
K217 | Ubiquitination | score1 | PhosphoSitePlus | |||
K223 | Ubiquitination | score1 | PhosphoSitePlus | |||
T232 | Phosphorylation | score1 | PhosphoSitePlus | |||
S249 | Phosphorylation | score1 | PhosphoSitePlus | |||
T260 | Phosphorylation | score1 | PhosphoSitePlus | |||
S285 | Phosphorylation | score1 | PhosphoSitePlus | |||
K289 | Ubiquitination | score1 | PhosphoSitePlus | |||
K297 | Ubiquitination | score1 | PhosphoSitePlus | |||
K308 | Acetylation | score1 | PhosphoSitePlus | |||
K308 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y313 | Phosphorylation | score1 | PhosphoSitePlus | |||
T315 | Phosphorylation | score1 | PhosphoSitePlus | |||
S320 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y6 | Phosphorylation | score0 | HPRD | 15144186, 20068231, 18707149 | ||
T84 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S88 | Phosphorylation | score0 | HPRD | 18669648, 15345747, 20068231 | ||
Y91 | Phosphorylation | score0 | HPRD | 19901323 | ||
T203 | Phosphorylation | score0 | HPRD | 20068231 | ||
T265 | Phosphorylation | score0 | HPRD | 20068231 | ||
T320 | Phosphorylation | score0 | HPRD | 15570572 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K65 | R65 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
R72 | H72 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R72 | C72 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T98 | I98 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T98 | A98 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
K102 | E102 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
S127 | L127 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
T198 | S198 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
T203 | S203 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |