iPTMnet Report for Q13291 (SLAMF1)
Protein Information
UniProt AC / UniProt ID | Q13291 / SLAF1_HUMAN |
Protein Name | Signaling lymphocytic activation molecule precursor |
Gene Name | Name: SLAMF1 Synonyms:SLAM; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q13291 |
PRO Name | signaling lymphocytic activation molecule (human) |
Definition | A SLAM family member 1 that is encoded in the genome of human. |
Short Label | hSLAMF1 |
Category | organism-gene |
Q13291 (SLAMF1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C32 | Methylation | score1 | IEDB | 31844290 | ||
S73 | Phosphorylation | score1 | PhosphoSitePlus | |||
N102 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N125 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
T272 | Phosphorylation | score1 | PhosphoSitePlus | |||
S277 | Phosphorylation | score1 | PhosphoSitePlus | |||
T279 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y281 | Phosphorylation | P06241 (FYN) | score4 | IntAct phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 11806999, 10549287, 11477068, ... | |
Y307 | Phosphorylation | P06239 (LCK) , P06241 (FYN) | score4 | IntAct phospho.ELM PhosphoSitePlus UniProt | 9774102, 11806999 | |
Y327 | Phosphorylation | P07948 (LYN) , P06241 (FYN) | score4 | phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 11806999, 11099315, 15315965 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S73 | N73 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T272 | A272 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T279 | K279 | Biomuta | DOID:363 / uterine cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
T279 | M279 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic, icgc ] | |
Y307 | C307 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |