iPTMnet Report Q13291 SLAMF1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q13291 / SLAF1_HUMAN
Protein Name	Signaling lymphocytic activation molecule precursor
Gene Name	Name: SLAMF1 Synonyms:SLAM;
Organism	Homo sapiens (Human)

PRO ID	PR:Q13291 DAG View
PRO Name	signaling lymphocytic activation molecule (human)
Definition	A SLAM family member 1 that is encoded in the genome of human.
Short Label	hSLAMF1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q13291 (SLAMF1) as Substrate

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	C32	Methylation		score1	IEDB	31844290
	S73	Phosphorylation		score1	PhosphoSitePlus
	N102	N-Glycosylation		score1	GlyGen	24190977
	N125	N-Glycosylation		score1	GlyGen	24190977
	T272	Phosphorylation		score1	PhosphoSitePlus
	S277	Phosphorylation		score1	PhosphoSitePlus
	T279	Phosphorylation		score1	PhosphoSitePlus
	Y281	Phosphorylation		score4	IntAct phospho.ELM PhosphoSitePlus RLIMS-P UniProt	11806999, 10549287, 11477068, ...11099315, 11313386, 18083107, 9774102, 10607564, 11689425, 11389028, 11823424, 14674764, 12545174, 12225753
	Y281	Phosphorylation	P06241 (FYN)	score3	phospho.ELM PhosphoSitePlus	11806999
	Y307	Phosphorylation		score4	IntAct phospho.ELM PhosphoSitePlus UniProt	9774102, 11806999
	Y307	Phosphorylation	P06239 (LCK)	score3	phospho.ELM PhosphoSitePlus	11806999
	Y307	Phosphorylation	P06241 (FYN)	score3	phospho.ELM PhosphoSitePlus	11806999
	Y327	Phosphorylation		score4	phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt	11806999, 11099315, 15315965
	Y327	Phosphorylation	P06241 (FYN)	score3	phospho.ELM PhosphoSitePlus	11806999
	Y327	Phosphorylation	P07948 (LYN)	score3	phospho.ELM PhosphoSitePlus Signor	15315965

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	Y281	Phosphorylation		score1	HPRD	11806999
	Y281	Phosphorylation	P06241 (FYN)	score1	HPRD	11806999
	Y307	Phosphorylation		score1	HPRD	11806999
	Y307	Phosphorylation	P06241 (FYN)	score1	HPRD	11806999
	Y327	Phosphorylation		score1	HPRD	11806999
	Y327	Phosphorylation	P06241 (FYN)	score1	HPRD	11806999

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S73	N73	Biomuta		DOID:4159 / skin cancer [ cosmic ]
T272	A272	Biomuta		DOID:3571 / liver cancer [ cosmic ]
T279	K279	Biomuta		DOID:363 / uterine cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
T279	M279	Biomuta		DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic, icgc ]
Y307	C307	Biomuta		DOID:2531 / hematologic cancer [ cosmic ]