Protein Information

Cytoscape View

UniProt AC / UniProt ID Q13227 / GPS2_HUMAN
Protein Name G protein pathway suppressor 2
Gene Name Name: GPS2
Organism Homo sapiens (Human)

PRO ID PR:Q13227
DAG View
PRO Name G protein pathway suppressor 2 (human)
Definition A G protein pathway suppressor 2 that is encoded in the genome of human.
Short Label hGPS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q13227 (GPS2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K66 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
R312 Methylation PhosphoSitePlus   UniProt 24129315
R323 Methylation PhosphoSitePlus   UniProt 24129315, 19917673

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K66 N66 Biomuta DOID:363 / uterine cancer [ tcga ]
K91 T91 Biomuta DOID:3070 / malignant glioma [ cosmic ]
K151 * Biomuta DOID:1612 / breast cancer [ cosmic ]
R312 W312 Biomuta DOID:1324 / lung cancer [ cosmic ]
R323 Q323 Biomuta DOID:1793 / pancreatic cancer [ tcga ] DOID:363 / uterine cancer [ tcga ]
R323 * Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]