iPTMnet Report for Q13114 (TRAF3)
Protein Information
UniProt AC / UniProt ID | Q13114 / TRAF3_HUMAN |
Protein Name | TNF receptor-associated factor 3 |
Gene Name | Name: TRAF3 Synonyms:CAP-1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q13114 |
PRO Name | TNF receptor-associated factor 3 (human) |
Definition | A TNF receptor-associated factor 3 that is encoded in the genome of human. |
Short Label | hTRAF3 |
Category | organism-gene |
Q13114 (TRAF3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S9 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T29 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y39 | Phosphorylation | score1 | PhosphoSitePlus | |||
S75 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y116 | Phosphorylation | score1 | PhosphoSitePlus | |||
K138 | Methylation | score1 | PhosphoSitePlus | |||
K154 | Ubiquitination | score1 | PhosphoSitePlus | |||
K168 | Ubiquitination | score3 | PhosphoSitePlus UniProt | 27438768 | ||
S275 | Phosphorylation | score1 | PhosphoSitePlus | |||
S281 | Phosphorylation | score1 | PhosphoSitePlus | |||
K329 | Ubiquitination | score1 | PhosphoSitePlus | |||
K335 | Ubiquitination | score1 | PhosphoSitePlus | |||
S349 | Phosphorylation | score1 | PhosphoSitePlus | |||
K351 | Ubiquitination | score1 | PhosphoSitePlus | |||
S356 | Phosphorylation | score1 | PhosphoSitePlus | |||
K369 | Ubiquitination | score1 | PhosphoSitePlus | |||
K429 | Ubiquitination | score1 | PhosphoSitePlus | |||
K436 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y446 | Phosphorylation | score1 | PhosphoSitePlus | |||
K513 | Ubiquitination | score1 | PhosphoSitePlus | |||
K557 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S9 | F9 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
T29 | M29 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:1319 / brain cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ] | |
T29 | P29 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
Y39 | C39 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
Y116 | C116 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K138 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S275 | F275 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc, tcga ] | |
S356 | F356 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
K436 | N436 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
Y446 | H446 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |