Protein Information

Cytoscape View

UniProt AC / UniProt ID Q13114 / TRAF3_HUMAN
Protein Name TNF receptor-associated factor 3
Gene Name Name: TRAF3
Organism Homo sapiens (Human)

PRO ID PR:Q13114
DAG View
PRO Name TNF receptor-associated factor 3 (human)
Definition A TNF receptor-associated factor 3 that is encoded in the genome of human.
Short Label hTRAF3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q13114 (TRAF3) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation PhosphoSitePlus   UniProt 23186163
T29 Phosphorylation PhosphoSitePlus
Y39 Phosphorylation PhosphoSitePlus
K138 Methylation PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
K557 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S9 F9 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
T29 M29 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:1324 / lung cancer [ cosmic ] DOID:3070 / malignant glioma [ tcga ]
Y39 C39 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ]
S275 F275 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S356 F356 Biomuta DOID:11934 / head and neck cancer [ tcga ]