iPTMnet Report for Q08999 (RBL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q08999 / RBL2_HUMAN
Protein Name Retinoblastoma-like protein 2
Gene Name Name: RBL2
Synonyms:RB2;
Organism Homo sapiens (Human)

PRO ID PR:Q08999
DAG View
PRO Name retinoblastoma-like protein 2 (human)
Definition A retinoblastoma-like protein 2 that is encoded in the genome of human.
Short Label hRBL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q08999 (RBL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S98 Phosphorylation PhosphoSitePlus
Y111 Phosphorylation PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
T115 Phosphorylation PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
T364 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
T401 Phosphorylation P11802 (CDK4) , Q00534 (CDK6) IEDB   phospho.ELM   PRO   PhosphoSitePlus   Signor 32897882, 32387766, 11157749
T404 Phosphorylation PhosphoSitePlus
S413 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   Signor   UniProt 23186163, 11157749
T417 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   Signor 11157749
S420 O-Glycosylation GlyGen 30379171, 28580691, 28571750, ...26960196
K443 Ubiquitination PhosphoSitePlus
S531 Phosphorylation PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus
Y544 Phosphorylation PhosphoSitePlus
S603 Phosphorylation PhosphoSitePlus
S639 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   Signor   UniProt 11042701, 11157749
T642 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   Signor 11157749
T647 Phosphorylation PhosphoSitePlus
S659 Phosphorylation Q9HC98 (NEK6) neXtProt   phospho.ELM   PhosphoSitePlus 12023960
T661 Phosphorylation PhosphoSitePlus
S662 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   Signor   UniProt 23186163, 19690332, 11157749
T664 Phosphorylation PhosphoSitePlus
T665 Phosphorylation PhosphoSitePlus
Y667 Phosphorylation PhosphoSitePlus
Y670 Phosphorylation PhosphoSitePlus
S672 Phosphorylation P11802 (CDK4) , Q00534 (CDK6) phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 12435635, 19690332, 11157749
S676 Phosphorylation PhosphoSitePlus
T678 Phosphorylation PhosphoSitePlus
S688 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   Signor   UniProt 23186163, 11157749
S690 Phosphorylation PhosphoSitePlus
T694 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   Signor 11157749
S941 Phosphorylation RLIMS-P 29606701
S948 Phosphorylation phospho.ELM   PhosphoSitePlus 11042701
S952 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   Signor   UniProt 11042701, 11157749
T954 Phosphorylation PhosphoSitePlus
T961 Phosphorylation PhosphoSitePlus
S962 Phosphorylation phospho.ELM   PhosphoSitePlus 11157749
S966 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 11042701
S971 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 11042701
S972 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 11042701
S973 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 11042701, 11157749
T974 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 11042701
S981 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 11042701
S982 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 11042701, 11157749
T986 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 11042701
T988 Phosphorylation PhosphoSitePlus
S995 Phosphorylation PhosphoSitePlus
T1019 Phosphorylation PhosphoSitePlus
S1035 Phosphorylation P11802 (CDK4) , Q00534 (CDK6) phospho.ELM   PRO   PhosphoSitePlus   Signor   UniProt 19690332, 11157749
Y1037 Phosphorylation PhosphoSitePlus
T1042 Phosphorylation PhosphoSitePlus
S1044 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   Signor 11157749
Y1057 Phosphorylation PhosphoSitePlus
S1059 Phosphorylation PhosphoSitePlus
T1065 Phosphorylation PhosphoSitePlus
S1068 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   Signor   UniProt 23186163, 11157749
S1078 Phosphorylation PhosphoSitePlus
S1080 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   Signor   UniProt 23186163, 11157749
S1082 Phosphorylation PhosphoSitePlus
S1090 Phosphorylation PhosphoSitePlus
T1097 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   Signor 11157749
S1112 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   Signor   UniProt 12006580, 23186163, 11157749
S1138 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T401 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
S413 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
T417 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
S639 Phosphorylation HPRD   PRO 19413330, 8710362, 11042701, ...11157749
T642 Phosphorylation HPRD   PRO 19413330, 8710362, 11042701, ...11157749
S662 Phosphorylation HPRD   PRO 20058876, 8710362, 11042701, ...11157749
S672 Phosphorylation HPRD   PRO 12006580, 8710362, 11042701, ...11157749
S688 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
T694 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
S948 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
S952 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
S962 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
S966 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
S971 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
S972 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
S973 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
T974 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
S981 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
S982 Phosphorylation HPRD   PRO 19413330, 8710362, 11042701, ...11157749
T986 Phosphorylation HPRD   PRO 19413330, 8710362, 11042701, ...11157749
S1035 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
S1044 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
S1068 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
S1080 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
T1097 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749
S1112 Phosphorylation HPRD   PRO 8710362, 11042701, 11157749


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049025 (hRBL2/Phos:4) pT401,pS672,pS1035 PRO
PR:000036471 (hRBL2/iso:1/Phos:1) pT401,pS413,pT417,pS639,pT642,pS662,pS672,pS688,pT694,pS948,pS952,pS962,pS966,pS973,pS982,pT986,pS1035,pS1044,pS1068,pS1080,pT1097,pS1112 PRO 11042701, 11157749, 8710362
PR:000036472 (hRBL2/iso:1/Phos:2) pS672 PRO 12006580
PR:000036473 (hRBL2/iso:1/Phos:3) pS639,pS952,pS966,pS971,pS972,pS973,pT974,pS981,pS982,pT986 PRO 11042701, 11157749, 8710362


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000036471 (hRBL2/iso:1/Phos:1) NOT Interaction PRO 11157749
PR:000036472 (hRBL2/iso:1/Phos:2) Interaction PR:Q13309 (hSKP2) PRO 12006580
PR:000036473 (hRBL2/iso:1/Phos:3) Interaction PR:Q16254 (hE2F4) PRO 11042701, 11157749
PR:Q08999-1 (hRBL2/iso:1) Interaction PRO 8361765